Photocatalytic Regioselective C-H Functionalization of Arenes: Advances, Mechanisms, and Applications
Fuente:
Zenodo
Salvato in:
| Autore principale: | |
|---|---|
| Natura: | Recurso digital |
| Pubblicazione: |
Zenodo
2025
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1866901343231279104 |
|---|---|
| author | Ajaysinh Vaghela*, Haval Chauhan |
| author_facet | Ajaysinh Vaghela*, Haval Chauhan |
| contents | <p><span lang="EN">The direct functionalization of aromatic C-H bonds has emerged as one of the most transformative strategies in modern organic synthesis, offering atom-economical approaches to molecular complexity. Photoredox catalysis has revolutionized this field by enabling selective C-H bond activation under mild reaction conditions through visible light irradiation. This review provides a comprehensive overview of recent advances in photocatalytic regioselective C-H functionalization of arenes, with particular emphasis on achieving ortho-, meta-, and para-selectivity. We discuss the mechanistic foundations underlying these transformations, including the role of transition metal catalysis, organic photocatalysts, and dual catalytic systems. The review covers major functional group installations including amination, oxygenation, cyanation, and other key transformations, highlighting their synthetic utility and mechanistic insights. Future directions and challenges in developing more efficient and selective photocatalytic systems are also addressed.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_17063329 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Photocatalytic Regioselective C-H Functionalization of Arenes: Advances, Mechanisms, and Applications Ajaysinh Vaghela*, Haval Chauhan Photoredox catalysis, C-H functionalization, regioselectivity, arene activation, dual catalysis <p><span lang="EN">The direct functionalization of aromatic C-H bonds has emerged as one of the most transformative strategies in modern organic synthesis, offering atom-economical approaches to molecular complexity. Photoredox catalysis has revolutionized this field by enabling selective C-H bond activation under mild reaction conditions through visible light irradiation. This review provides a comprehensive overview of recent advances in photocatalytic regioselective C-H functionalization of arenes, with particular emphasis on achieving ortho-, meta-, and para-selectivity. We discuss the mechanistic foundations underlying these transformations, including the role of transition metal catalysis, organic photocatalysts, and dual catalytic systems. The review covers major functional group installations including amination, oxygenation, cyanation, and other key transformations, highlighting their synthetic utility and mechanistic insights. Future directions and challenges in developing more efficient and selective photocatalytic systems are also addressed.</span></p> |
| title | Photocatalytic Regioselective C-H Functionalization of Arenes: Advances, Mechanisms, and Applications |
| topic | Photoredox catalysis, C-H functionalization, regioselectivity, arene activation, dual catalysis |
| url | https://doi.org/10.5281/zenodo.17063329 |