Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes

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Main Author: Reimand, Jüri
Format: Recurso digital
Published: Zenodo 2025
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author Reimand, Jüri
author_facet Reimand, Jüri
contents <p>This repository contains R software packages of main algorithms used in the study:</p> <p>"Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes" (2025) by Liis Uusküla-Reimand, Christian A. Lee, Robin H. Oh, Zoe P. Klein, Nina Adler, Sana Akhtar Alvi, Ellen Langille, Elisa Pasini, Kevin C. L. Cheng, Evgenija Serafimova, Diala Abd-Rabbo, Huayun Hou, Ricky Tsai, Mamatha Bhat, Daniel Schramek, Michael D. Wilson, Jüri Reimand. </p> <p>The software packages include ActiveDriverWGS (https://github.com/reimandlab/ActiveDriverWGSR; v1.2.0), ActivePathways (https://github.com/reimandlab/ActivePathways; v2.0.3), and RM2 (https://github.com/reimandlab/RM2; v2022-08-11).</p> <p>Preprint of the study is available in bioRxiv (https://www.biorxiv.org/content/10.1101/2024.11.06.622320v1). </p>
format Recurso digital
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institution Zenodo
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publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes
Reimand, Jüri
<p>This repository contains R software packages of main algorithms used in the study:</p> <p>"Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes" (2025) by Liis Uusküla-Reimand, Christian A. Lee, Robin H. Oh, Zoe P. Klein, Nina Adler, Sana Akhtar Alvi, Ellen Langille, Elisa Pasini, Kevin C. L. Cheng, Evgenija Serafimova, Diala Abd-Rabbo, Huayun Hou, Ricky Tsai, Mamatha Bhat, Daniel Schramek, Michael D. Wilson, Jüri Reimand. </p> <p>The software packages include ActiveDriverWGS (https://github.com/reimandlab/ActiveDriverWGSR; v1.2.0), ActivePathways (https://github.com/reimandlab/ActivePathways; v2.0.3), and RM2 (https://github.com/reimandlab/RM2; v2022-08-11).</p> <p>Preprint of the study is available in bioRxiv (https://www.biorxiv.org/content/10.1101/2024.11.06.622320v1). </p>
title Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes
url https://doi.org/10.5281/zenodo.17154325