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| Format: | Recurso digital |
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Zenodo
2025
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| Online Access: | https://doi.org/10.5281/zenodo.17158260 |
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Table of Contents:
- <h2>About</h2> <p><br>MATLAB custom codes used in Peng et al. Nature Communications 2025.</p> <p>*Calculate the dissociation constant (KD) from the fitting results of the pair-cross correlation function <br>(1) KD calculation for homodimerization <br>Run “KD_calc_master_homo.m” and the results are generated as “KD”.</p> <p>(2) KD calculation for heterodimerization <br>Run “KD_calc_master_hetero.m” and the results are generated in the root folder. </p> <p>*Simulate the pair-cross correlation function (PCCF) with the given kinetic parameters <br>(3) PCCF simulation for homodimerization <br>Run “ColSimu_master_homo.m” and the results are generated in the “Results” folder.</p> <p>(4) PCCF simulation for heterodimerization <br>Run “ColSimu_master_hetero.m” and the results are generated in the “Results” folder.</p> <h2> </h2> <h2><br>Required MATLAB toolbox</h2> <p><br>Curve Fitting Toolbox, Parallel Computing Toolbox, Statistics and Machine Learning Toolbox, Symbolic Math Toolbox</p> <h2> </h2> <h2><br>Copyright</h2> <p><br>2025 T.A. Tsunoyama, P. Zhou, and A. Kusumi, Membrane Cooperativity Unit, Okinawa Institute of Science and Technology. <br>All rights reserved. <br>Unauthorized modification, reproduction, or distribution of this program, or any portion of it, is strictly prohibited.</p> <h2> </h2> <h2><br>Reference</h2> <p><br>Single-molecule detection of transient dimerization of opioid receptors 1: Homodimers’ effect on signaling and internalization <br>Peng Zhou, Taka A. Tsunoyama, Rinshi S. Kasai, Koichiro M. Hirosawa, Ziya Kalay, Amine Aladag, Takahiro K. Fujiwara, Simone Pigolotti, Akihiro Kusumi <br>bioRxiv 2024.07.25.605080; doi: https://doi.org/10.1101/2024.07.25.605080 <br> <br>Single-molecule detection of transient dimerization of opioid receptors 2: Heterodimer blockage reduces morphine tolerance <br>Peng Zhou, Rinshi S. Kasai, Wakako Fujita, Taka A. Tsunoyama, Hiroshi Ueda, Simone Pigolotti, Takahiro K. Fujiwara, Akihiro Kusumi <br>bioRxiv 2024.07.25.605109; doi: https://doi.org/10.1101/2024.07.25.605109 </p>