Global Haplotype Landscape of SARS-CoV-2 Spike Contact Residues Reveals Dominant Escape Signatures and Systemic Sequencing Ambiguity
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| Format: | Recurso digital |
| Langue: | anglais |
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Zenodo
2025
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| _version_ | 1866902119143964672 |
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| author | Bhatti, Tahir |
| author_facet | Bhatti, Tahir |
| contents | <p>Audit of 4.5M SARS-CoV-2 <strong>contact residue haplotypes </strong>(20 positions, 60 nt each) extracted from global genomes.</p> <p>All sequences length-validated (60 nt).</p> <p>Top haplotype (1M+ copies) encodes Omicron signature (N417, G446, Y449...). 5.64% N-content highlights technical dropout at hypervariable sites.</p> <p>11k duplicated haplotypes enable lineage tracking.</p> <p>Includes full report, translated top variants, reproducible scripts.</p> <p>Privately uploaded for job applications - available upon request.</p> <p>Derived from real public data. </p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_17161331 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Global Haplotype Landscape of SARS-CoV-2 Spike Contact Residues Reveals Dominant Escape Signatures and Systemic Sequencing Ambiguity Bhatti, Tahir SARS-CoV-2 Spike Contact Residues 5 Angstrom <p>Audit of 4.5M SARS-CoV-2 <strong>contact residue haplotypes </strong>(20 positions, 60 nt each) extracted from global genomes.</p> <p>All sequences length-validated (60 nt).</p> <p>Top haplotype (1M+ copies) encodes Omicron signature (N417, G446, Y449...). 5.64% N-content highlights technical dropout at hypervariable sites.</p> <p>11k duplicated haplotypes enable lineage tracking.</p> <p>Includes full report, translated top variants, reproducible scripts.</p> <p>Privately uploaded for job applications - available upon request.</p> <p>Derived from real public data. </p> |
| title | Global Haplotype Landscape of SARS-CoV-2 Spike Contact Residues Reveals Dominant Escape Signatures and Systemic Sequencing Ambiguity |
| topic | SARS-CoV-2 Spike Contact Residues 5 Angstrom |
| url | https://doi.org/10.5281/zenodo.17161331 |