REAL-TIME PCR DETECTION OF RABIES VIRUS EMPLOYING SYBR GREEN DYE

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Autor principal: Harpreet, Singh Dhillon
Formato: Recurso digital
Lenguaje:inglés
Publicado: Zenodo 2025
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author Harpreet, Singh Dhillon
author_facet Harpreet, Singh Dhillon
contents <p><em><span>The present study was envisaged to compare the sensitivity of SYBR Green real time PCR with immunofluorescence PCR for diagnosis of rabies. SYBR Green real time PCR technique was applied on brain samples collected from 39 rabies suspected animals. Sensitivity of SYBR Green technique was compared in accordance with WHO recommended gold standard test viz. Fluorescent Antibody Technique (FAT) applied on brain samples. SYBR Green real time PCR applied on brain samples had successfully confirmed rabies in 16/39 with a Sensitivity of 80%. It was concluded that SYBR Green real time PCR is a useful, specific, sensitive and better molecular approach for diagnosis of rabies from brain of rabid suspected cases and can be used as confirmatory test for rabies diagnosis. </span></em></p> <p><strong><span> </span></strong></p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_17199672
institution Zenodo
language eng
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle REAL-TIME PCR DETECTION OF RABIES VIRUS EMPLOYING SYBR GREEN DYE
Harpreet, Singh Dhillon
Brain, Molecular, Rabies, Real time PCR, SYBR Green.
<p><em><span>The present study was envisaged to compare the sensitivity of SYBR Green real time PCR with immunofluorescence PCR for diagnosis of rabies. SYBR Green real time PCR technique was applied on brain samples collected from 39 rabies suspected animals. Sensitivity of SYBR Green technique was compared in accordance with WHO recommended gold standard test viz. Fluorescent Antibody Technique (FAT) applied on brain samples. SYBR Green real time PCR applied on brain samples had successfully confirmed rabies in 16/39 with a Sensitivity of 80%. It was concluded that SYBR Green real time PCR is a useful, specific, sensitive and better molecular approach for diagnosis of rabies from brain of rabid suspected cases and can be used as confirmatory test for rabies diagnosis. </span></em></p> <p><strong><span> </span></strong></p>
title REAL-TIME PCR DETECTION OF RABIES VIRUS EMPLOYING SYBR GREEN DYE
topic Brain, Molecular, Rabies, Real time PCR, SYBR Green.
url https://doi.org/10.5281/zenodo.17199672