DOSE-DEPENDENT EFFECT OF AQUEOUS EXTRACT OF JATROPHA TANJORENSIS (CHAYA) LEAF ON BIOCHEMICAL MARKERS IN MALE WISTER RATS
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| author | Dim Catherine Nicholate Ezeokafor Emmanuel Nonso Enendu Angela Chika Charles Chinemeze Anyaogu Afuberoh Francis Chukwudi Anyiam Kennedy Ekenedirichukwu Okoye Ogochukwu Fidelis |
| author_facet | Dim Catherine Nicholate Ezeokafor Emmanuel Nonso Enendu Angela Chika Charles Chinemeze Anyaogu Afuberoh Francis Chukwudi Anyiam Kennedy Ekenedirichukwu Okoye Ogochukwu Fidelis |
| contents | <p><strong><span>Abstract:</span></strong><span> <span>Many traditionally known medicinal plants studied in the last few decades have been reported to possess various medicinal properties such as anticancer activity, antioxidant activity, anti-inflammatory, anti-diabetic, antibacterial, antifungal and hepato-protective activities. This study aimed to evaluate the effect of aqueous extract of dose- dependent <em>Jatropha tanjorensis </em>(chaya) leaf on biochemical parameters of male wistar rats. Total of<span> </span>forty (40) male wister rats weighing 130-150g (about 12 weeks old) were grouped into five groups of 8 rats each, (group A to E), Group A served as negative control ( just water and feed only),while Group B (Low dose of Jatropha tanjorensis,200mg/kg),Group C (Medium dose of <em>Jatropha tanjorensis </em>,400mg/kg), Group D, (High dose of <a name="_Hlk193884802"></a>Jatropha tanjorensis, 600mg/kg), Group E (Positive control ,just folic acid drugs and feed only). Biochemical parameters were accessed. The study findings revealed that the aqueous extract of <em>Jatropha tanjorensis </em>leaves, when administered to the experimental rats, showed a significant decrease in serum creatine levels in treatment groups B, C, and D. As well as in AST, ALP and ALT levels increased in all the groups(P<0.05).</span></span></p> <p><strong><span>Keywords:</span></strong><span> Biochemical, Extract, Jatropha tanjorensis, Medicinal, Wistar rats.</span><em><span> </span></em></p> <p><strong><span lang="EN-US">Title:</span></strong> <span>DOSE-DEPENDENT EFFECT OF AQUEOUS EXTRACT OF <em>JATROPHA TANJORENSIS </em></span><span>(<span>CHAYA) LEAF</span> <span>ON BIOCHEMICAL MARKERS IN MALE WISTER RATS</span></span></p> <p><strong><span lang="EN-US">Author:</span></strong><span lang="EN-US"> Dim Catherine Nicholate, Ezeokafor Emmanuel Nonso, Enendu Angela Chika, Charles Chinemeze Anyaogu, Afuberoh Francis Chukwudi, Anyiam Kennedy Ekenedirichukwu, Okoye Ogochukwu Fidelis</span></p> <p><strong><span lang="EN-US">International Journal of Recent Research in Life Sciences (IJRRLS)</span></strong></p> <p><strong><span lang="EN-US">ISSN 2349-7823</span></strong></p> <p><strong><span lang="EN-US">Vol. 12, Issue 4, October 2025 - December 2025</span></strong></p> <p><strong><span lang="EN-US">Page No: 1-4</span></strong></p> <p><strong><span lang="EN-US">Paper Publications</span></strong></p> <p><strong><span lang="EN-US">Website: www.paperpublications.org</span></strong></p> <p><strong><span lang="EN-US">Published Date: 06-October-2025</span></strong></p> <p><strong><span lang="EN-US">DOI: <a href="https://doi.org/10.5281/zenodo.17278799">https://doi.org/10.5281/zenodo.17278799</a></span></strong></p> <p><strong><span lang="EN-US">Paper Download Link (Source)</span></strong></p> <p><strong><span lang="EN-US"><a href="https://www.paperpublications.org/upload/book/DOSE-DEPENDENT%20EFFECT%20OF%20AQUEOUS-06102025-3.pdf">https://www.paperpublications.org/upload/book/DOSE-DEPENDENT%20EFFECT%20OF%20AQUEOUS-06102025-3.pdf</a></span></strong></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_17278799 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | DOSE-DEPENDENT EFFECT OF AQUEOUS EXTRACT OF JATROPHA TANJORENSIS (CHAYA) LEAF ON BIOCHEMICAL MARKERS IN MALE WISTER RATS Dim Catherine Nicholate Ezeokafor Emmanuel Nonso Enendu Angela Chika Charles Chinemeze Anyaogu Afuberoh Francis Chukwudi Anyiam Kennedy Ekenedirichukwu Okoye Ogochukwu Fidelis Biochemical Extract Jatropha tanjorensis Wistar rats <p><strong><span>Abstract:</span></strong><span> <span>Many traditionally known medicinal plants studied in the last few decades have been reported to possess various medicinal properties such as anticancer activity, antioxidant activity, anti-inflammatory, anti-diabetic, antibacterial, antifungal and hepato-protective activities. This study aimed to evaluate the effect of aqueous extract of dose- dependent <em>Jatropha tanjorensis </em>(chaya) leaf on biochemical parameters of male wistar rats. Total of<span> </span>forty (40) male wister rats weighing 130-150g (about 12 weeks old) were grouped into five groups of 8 rats each, (group A to E), Group A served as negative control ( just water and feed only),while Group B (Low dose of Jatropha tanjorensis,200mg/kg),Group C (Medium dose of <em>Jatropha tanjorensis </em>,400mg/kg), Group D, (High dose of <a name="_Hlk193884802"></a>Jatropha tanjorensis, 600mg/kg), Group E (Positive control ,just folic acid drugs and feed only). Biochemical parameters were accessed. The study findings revealed that the aqueous extract of <em>Jatropha tanjorensis </em>leaves, when administered to the experimental rats, showed a significant decrease in serum creatine levels in treatment groups B, C, and D. As well as in AST, ALP and ALT levels increased in all the groups(P<0.05).</span></span></p> <p><strong><span>Keywords:</span></strong><span> Biochemical, Extract, Jatropha tanjorensis, Medicinal, Wistar rats.</span><em><span> </span></em></p> <p><strong><span lang="EN-US">Title:</span></strong> <span>DOSE-DEPENDENT EFFECT OF AQUEOUS EXTRACT OF <em>JATROPHA TANJORENSIS </em></span><span>(<span>CHAYA) LEAF</span> <span>ON BIOCHEMICAL MARKERS IN MALE WISTER RATS</span></span></p> <p><strong><span lang="EN-US">Author:</span></strong><span lang="EN-US"> Dim Catherine Nicholate, Ezeokafor Emmanuel Nonso, Enendu Angela Chika, Charles Chinemeze Anyaogu, Afuberoh Francis Chukwudi, Anyiam Kennedy Ekenedirichukwu, Okoye Ogochukwu Fidelis</span></p> <p><strong><span lang="EN-US">International Journal of Recent Research in Life Sciences (IJRRLS)</span></strong></p> <p><strong><span lang="EN-US">ISSN 2349-7823</span></strong></p> <p><strong><span lang="EN-US">Vol. 12, Issue 4, October 2025 - December 2025</span></strong></p> <p><strong><span lang="EN-US">Page No: 1-4</span></strong></p> <p><strong><span lang="EN-US">Paper Publications</span></strong></p> <p><strong><span lang="EN-US">Website: www.paperpublications.org</span></strong></p> <p><strong><span lang="EN-US">Published Date: 06-October-2025</span></strong></p> <p><strong><span lang="EN-US">DOI: <a href="https://doi.org/10.5281/zenodo.17278799">https://doi.org/10.5281/zenodo.17278799</a></span></strong></p> <p><strong><span lang="EN-US">Paper Download Link (Source)</span></strong></p> <p><strong><span lang="EN-US"><a href="https://www.paperpublications.org/upload/book/DOSE-DEPENDENT%20EFFECT%20OF%20AQUEOUS-06102025-3.pdf">https://www.paperpublications.org/upload/book/DOSE-DEPENDENT%20EFFECT%20OF%20AQUEOUS-06102025-3.pdf</a></span></strong></p> |
| title | DOSE-DEPENDENT EFFECT OF AQUEOUS EXTRACT OF JATROPHA TANJORENSIS (CHAYA) LEAF ON BIOCHEMICAL MARKERS IN MALE WISTER RATS |
| topic | Biochemical Extract Jatropha tanjorensis Wistar rats |
| url | https://doi.org/10.5281/zenodo.17278799 |