Spatial-Immune Multi-omics Refines Prognostication in Early-Stage Estrogen Receptor-Positive Breast Cancer

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Autor principal: Kinsella, Zak
Formato: Recurso digital
Lenguaje:inglés
Publicado: Zenodo 2025
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author Kinsella, Zak
author_facet Kinsella, Zak
contents <p>Raw CSV files containing source data for the modalities used in the corresponding study. A brief description of each CSV file:<br>(1) 'TAILORx_Patient_TIL' contains percentages ('_per_pos') and densities for subject-level queries.<br>(2) 'TAILORx_Patient_TIL_SingleCell' contains information on Euclidean pairwise distances of each detected phenotype, and distances of each phenotype from an epithelial boundary (i.e. tumour mask). </p> <p>(3) 'TAILORx_Patient_TIL_Omics' contains information on ROI-level immune counts and z-score normalised genes for stroma (TME) and epithelia (tumour) for each available patient. As one TMA core was used per patient for this analysis, proteomics immune phenotype percentages and densities for that core are attached. </p> <p>(4) 'TAILORx_Patient_CD8_IHC' contains information on CD8 IHC data for whole-slide images. </p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_17288210
institution Zenodo
language eng
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle Spatial-Immune Multi-omics Refines Prognostication in Early-Stage Estrogen Receptor-Positive Breast Cancer
Kinsella, Zak
<p>Raw CSV files containing source data for the modalities used in the corresponding study. A brief description of each CSV file:<br>(1) 'TAILORx_Patient_TIL' contains percentages ('_per_pos') and densities for subject-level queries.<br>(2) 'TAILORx_Patient_TIL_SingleCell' contains information on Euclidean pairwise distances of each detected phenotype, and distances of each phenotype from an epithelial boundary (i.e. tumour mask). </p> <p>(3) 'TAILORx_Patient_TIL_Omics' contains information on ROI-level immune counts and z-score normalised genes for stroma (TME) and epithelia (tumour) for each available patient. As one TMA core was used per patient for this analysis, proteomics immune phenotype percentages and densities for that core are attached. </p> <p>(4) 'TAILORx_Patient_CD8_IHC' contains information on CD8 IHC data for whole-slide images. </p>
title Spatial-Immune Multi-omics Refines Prognostication in Early-Stage Estrogen Receptor-Positive Breast Cancer
url https://doi.org/10.5281/zenodo.17288210