Saved in:
| Main Author: | |
|---|---|
| Format: | Recurso digital |
| Language: | |
| Published: |
Zenodo
2025
|
| Online Access: | https://doi.org/10.5281/zenodo.17359791 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1866901268509753344 |
|---|---|
| author | Dalvi, Nilesh |
| author_facet | Dalvi, Nilesh |
| contents | <p><strong><span lang="EN-US">Abstract</span></strong></p> <p><strong><span lang="EN-US">Background:</span></strong></p> <p><span lang="EN-US">Obesity and insulin resistance represent global metabolic challenges. Ayurveda, through Charaka <em>Saṃhitā</em><sup>[1]</sup>, recognized obesity <em>(Sthaulya/Atisthūlya)</em> as a serious pathological state and listed eight defects (Ashta <em>Doṣas</em>) associated with it: Ā<em>yuṣo hrāsaḥ, Jāvo’parodhaḥ, Kṛcchra-vyavāyatā, Daurbalyaṃ, Daurgandhyaṃ, Svedābādhaḥ, Ati-ślathatā, Ati-pipāsā ca </em><sup>[2]</sup>. This study explores the conceptual parallels between these eight classical features and the biomedical pathophysiology of insulin resistance (IR)<sup> [3]</sup>. Each of the eight defects is correlated with contemporary medical understanding of metabolic dysfunction and energy imbalance.<sup> [4]</sup></span></p> <p><strong><span lang="EN-US">Objectives:</span></strong></p> <p><span lang="EN-US">To analyze Charaka’s Ashta <em>Doṣas </em>of<em> Atisthūlya</em> from an Ayurvedic and biomedical perspective.</span></p> <p><span lang="EN-US">To correlate these with modern clinical manifestations of insulin resistance and obesity-related metabolic syndrome.</span></p> <p><strong><span lang="EN-US">Methods:</span></strong><span lang="EN-US">A narrative comparative review was performed using Ayurvedic classical texts <em>(Charaka Saṃhitā, Sushruta Saṃhitā, Ashtāṅga Hṛdaya) </em>and modern biomedical literature (PubMed, Google Scholar). The eight classical defects were interpreted through Ayurvedic commentaries and mapped against established pathophysiologic features and complications of insulin resistance.</span></p> <p><strong><span lang="EN-US">Results:</span></strong><span lang="EN-US"> Each of the eight classical defects of <em>Atisthūlya</em> described by <em>Āchārya</em> <em>Charaka</em> closely corresponds to biomedical manifestations of insulin resistance, such as reduced longevity, decreased physical capacity, sexual dysfunction, fatigue, body odour, excessive sweating, tissue laxity, and excessive thirst—all common in metabolic syndrome and type 2 diabetes mellitus.</span></p> <p><strong><span lang="EN-US">Conclusion: </span></strong><span lang="EN-US">Charaka’s description of <em>Atisthūlya</em> remarkably parallels the systemic complications of insulin resistance. This highlights Ayurveda’s sophisticated understanding of metabolic imbalance and provides a conceptual bridge for integrative preventive and therapeutic research.</span></p> <p><span lang="EN-US"> </span></p> <p><span lang="EN-US"><span> </span><strong>Keywords:</strong> <em>Ayurveda, Sthaulya, Atisthūlya</em>, Insulin resistance, <em>Medoroga</em>, Metabolic syndrome, Ashta Doṣa</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_17359791 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Comparative Study On Insulin Resistance And The Eight Problems Of Obesity (Atisthulya) As Described In Ayurveda With Special Reference To Charaka Samhita Dalvi, Nilesh <p><strong><span lang="EN-US">Abstract</span></strong></p> <p><strong><span lang="EN-US">Background:</span></strong></p> <p><span lang="EN-US">Obesity and insulin resistance represent global metabolic challenges. Ayurveda, through Charaka <em>Saṃhitā</em><sup>[1]</sup>, recognized obesity <em>(Sthaulya/Atisthūlya)</em> as a serious pathological state and listed eight defects (Ashta <em>Doṣas</em>) associated with it: Ā<em>yuṣo hrāsaḥ, Jāvo’parodhaḥ, Kṛcchra-vyavāyatā, Daurbalyaṃ, Daurgandhyaṃ, Svedābādhaḥ, Ati-ślathatā, Ati-pipāsā ca </em><sup>[2]</sup>. This study explores the conceptual parallels between these eight classical features and the biomedical pathophysiology of insulin resistance (IR)<sup> [3]</sup>. Each of the eight defects is correlated with contemporary medical understanding of metabolic dysfunction and energy imbalance.<sup> [4]</sup></span></p> <p><strong><span lang="EN-US">Objectives:</span></strong></p> <p><span lang="EN-US">To analyze Charaka’s Ashta <em>Doṣas </em>of<em> Atisthūlya</em> from an Ayurvedic and biomedical perspective.</span></p> <p><span lang="EN-US">To correlate these with modern clinical manifestations of insulin resistance and obesity-related metabolic syndrome.</span></p> <p><strong><span lang="EN-US">Methods:</span></strong><span lang="EN-US">A narrative comparative review was performed using Ayurvedic classical texts <em>(Charaka Saṃhitā, Sushruta Saṃhitā, Ashtāṅga Hṛdaya) </em>and modern biomedical literature (PubMed, Google Scholar). The eight classical defects were interpreted through Ayurvedic commentaries and mapped against established pathophysiologic features and complications of insulin resistance.</span></p> <p><strong><span lang="EN-US">Results:</span></strong><span lang="EN-US"> Each of the eight classical defects of <em>Atisthūlya</em> described by <em>Āchārya</em> <em>Charaka</em> closely corresponds to biomedical manifestations of insulin resistance, such as reduced longevity, decreased physical capacity, sexual dysfunction, fatigue, body odour, excessive sweating, tissue laxity, and excessive thirst—all common in metabolic syndrome and type 2 diabetes mellitus.</span></p> <p><strong><span lang="EN-US">Conclusion: </span></strong><span lang="EN-US">Charaka’s description of <em>Atisthūlya</em> remarkably parallels the systemic complications of insulin resistance. This highlights Ayurveda’s sophisticated understanding of metabolic imbalance and provides a conceptual bridge for integrative preventive and therapeutic research.</span></p> <p><span lang="EN-US"> </span></p> <p><span lang="EN-US"><span> </span><strong>Keywords:</strong> <em>Ayurveda, Sthaulya, Atisthūlya</em>, Insulin resistance, <em>Medoroga</em>, Metabolic syndrome, Ashta Doṣa</span></p> |
| title | Comparative Study On Insulin Resistance And The Eight Problems Of Obesity (Atisthulya) As Described In Ayurveda With Special Reference To Charaka Samhita |
| url | https://doi.org/10.5281/zenodo.17359791 |