EVALUATION OF PHYSICAL PARAMETERS OF LOCALLY MANUFACTURED AND IMPORTED DEXAMETHASONE 0.1% OPHTHALMIC DROPS IN KABUL CITY

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Main Authors: Azimullah Wafa*, Rohullah Yousofazai, Ziarmal Teerzai, Roshaan Raihan, Najiburahman Rahmani, Mohiburahman Haleem
Format: Recurso digital
Language:English
Published: Zenodo 2025
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author Azimullah Wafa*
Rohullah Yousofazai
Ziarmal Teerzai
Roshaan Raihan
Najiburahman Rahmani
Mohiburahman Haleem
author_facet Azimullah Wafa*
Rohullah Yousofazai
Ziarmal Teerzai
Roshaan Raihan
Najiburahman Rahmani
Mohiburahman Haleem
contents <p><span lang="EN-IN">Background: Dexamethasone 0.1% ophthalmic drops are widely used for ocular therapy. Physical parameters like drop volume, pH, and packaging integrity are critical for safe use. Objective: To evaluate the physical characteristics of locally manufactured and imported Dexamethasone 0.1% ophthalmic drops available in Kabul. Methods: Seven brands were collected from local pharmacies. Dropper calibration, total volume, pH, and labeling were evaluated according to British Pharmacopoeia (2023) standards. Results: Most samples met pharmacopeia standards. Samples F<sub>6</sub> failed volume criteria; samples F<sub>2</sub>, F<sub>4</sub>, F<sub>5</sub>, and F<sub>6</sub> exceeded acceptable pH limits. Packaging deficiencies were noted in F<sub>1</sub> and F<sub>3</sub>. Conclusion: While most drops were compliant, a few posed risks due to pH or volume deviations. Strict quality control is recommended.</span></p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_17484115
institution Zenodo
language eng
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle EVALUATION OF PHYSICAL PARAMETERS OF LOCALLY MANUFACTURED AND IMPORTED DEXAMETHASONE 0.1% OPHTHALMIC DROPS IN KABUL CITY
Azimullah Wafa*
Rohullah Yousofazai
Ziarmal Teerzai
Roshaan Raihan
Najiburahman Rahmani
Mohiburahman Haleem
Dexamethasone 0.1%
ophthalmic drops
physical evaluation
pH
dropper calibration
<p><span lang="EN-IN">Background: Dexamethasone 0.1% ophthalmic drops are widely used for ocular therapy. Physical parameters like drop volume, pH, and packaging integrity are critical for safe use. Objective: To evaluate the physical characteristics of locally manufactured and imported Dexamethasone 0.1% ophthalmic drops available in Kabul. Methods: Seven brands were collected from local pharmacies. Dropper calibration, total volume, pH, and labeling were evaluated according to British Pharmacopoeia (2023) standards. Results: Most samples met pharmacopeia standards. Samples F<sub>6</sub> failed volume criteria; samples F<sub>2</sub>, F<sub>4</sub>, F<sub>5</sub>, and F<sub>6</sub> exceeded acceptable pH limits. Packaging deficiencies were noted in F<sub>1</sub> and F<sub>3</sub>. Conclusion: While most drops were compliant, a few posed risks due to pH or volume deviations. Strict quality control is recommended.</span></p>
title EVALUATION OF PHYSICAL PARAMETERS OF LOCALLY MANUFACTURED AND IMPORTED DEXAMETHASONE 0.1% OPHTHALMIC DROPS IN KABUL CITY
topic Dexamethasone 0.1%
ophthalmic drops
physical evaluation
pH
dropper calibration
url https://doi.org/10.5281/zenodo.17484115