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| Format: | Recurso digital |
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Zenodo
2025
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| Online-Zugang: | https://doi.org/10.5281/zenodo.17573742 |
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Inhaltsangabe:
- <h1>MERFISHEYES Single-Cell Visualizer</h1> <p>Interactive web-based tool for exploring zebrafish embryonic development with integrated scRNA-seq, scATAC-seq, and MERFISH spatial transcriptomics data.</p> <h2>Features</h2> <ul> <li><strong>3D Spatial Visualization</strong>: Interactive Three.js-based visualization of cells in spatial coordinates</li> <li><strong>Multi-Modal Data</strong>: Toggle between RNA expression and chromatin accessibility views</li> <li><strong>Latent Space Exploration</strong>: View cells in UMAP embeddings</li> <li><strong>Interactive Filtering</strong>: Filter by cell type, genes, and ATAC-seq peaks</li> <li><strong>Developmental Trajectories</strong>: Explore zebrafish development from gastrulation to organogenesis</li> <li><strong>Responsive UI</strong>: Bootstrap-based interface with dynamic color scales and controls</li> </ul> <h2>Data Source</h2> <p>Data from <strong>Wan et al.</strong> (2024) - Whole-embryo Spatial Transcriptomics at Subcellular Resolution from Gastrulation to Organogenesis</p> <ul> <li>DOI: <a href="https://doi.org/10.1101/2024.08.27.609868">10.1101/2024.08.27.609868</a></li> </ul> <h2>Tech Stack</h2> <ul> <li>Vite 5.x</li> <li>Three.js for 3D rendering</li> <li>Bootstrap 5 for UI</li> <li>RxJS for reactive state management</li> <li>jQuery for DOM manipulation</li> </ul>