IMPROVEMENT OF IMMUNOHEMATOLOGICAL CHARACTERISTICS AND PROPHYLAXIS OF COMORBID HEMORRHAGIC VASCULITIS AND NEPHROPATHY IN CHILDREN
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2025
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| _version_ | 1866901880544690176 |
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| author | Mamadaliyeva, Hilolaxon |
| author_facet | Mamadaliyeva, Hilolaxon |
| contents | <p><span lang="EN-US">The comorbid course of hemorrhagic vasculitis (Henoch–Schönlein purpura) and nephropathy in children is associated with more severe clinical manifestations and profound immune-hematological disturbances. The study investigated immune and hematological parameters (IgA, IgG, IgM, CD4+/CD8+ ratio, complement C3, and blood indices). Results revealed elevated IgA levels, activation of the complement system, and a reduced CD4+/CD8+ ratio. The improved preventive program — including immunomodulatory therapy and long-term follow-up — reduced relapse frequency and preserved renal function in affected children.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_17593079 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | IMPROVEMENT OF IMMUNOHEMATOLOGICAL CHARACTERISTICS AND PROPHYLAXIS OF COMORBID HEMORRHAGIC VASCULITIS AND NEPHROPATHY IN CHILDREN Mamadaliyeva, Hilolaxon hemorrhagic vasculitis, nephropathy, children, immune system, hematology, prevention, comorbidity <p><span lang="EN-US">The comorbid course of hemorrhagic vasculitis (Henoch–Schönlein purpura) and nephropathy in children is associated with more severe clinical manifestations and profound immune-hematological disturbances. The study investigated immune and hematological parameters (IgA, IgG, IgM, CD4+/CD8+ ratio, complement C3, and blood indices). Results revealed elevated IgA levels, activation of the complement system, and a reduced CD4+/CD8+ ratio. The improved preventive program — including immunomodulatory therapy and long-term follow-up — reduced relapse frequency and preserved renal function in affected children.</span></p> |
| title | IMPROVEMENT OF IMMUNOHEMATOLOGICAL CHARACTERISTICS AND PROPHYLAXIS OF COMORBID HEMORRHAGIC VASCULITIS AND NEPHROPATHY IN CHILDREN |
| topic | hemorrhagic vasculitis, nephropathy, children, immune system, hematology, prevention, comorbidity |
| url | https://doi.org/10.5281/zenodo.17593079 |