Antibacterial activity of fennel (Foeniculum vulgare) leaf from the slopes of Mount Bromo against Methicillin-resistant Staphylococcus aureus

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Main Authors: Rahmah, Anindya Fatihatur, Koendhori, Eko Budi, Susanto, Joni
Format: Recurso digital
Language:English
Published: Zenodo 2025
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author Rahmah, Anindya Fatihatur
Koendhori, Eko Budi
Susanto, Joni
author_facet Rahmah, Anindya Fatihatur
Koendhori, Eko Budi
Susanto, Joni
contents <p>Staphylococcus aureus is an infection-causing bacterium that is associated with many deaths in the world and is complicated by its adaptable condition that causes cases of antibiotic resistance. Fennel (Foeniculum vulgare) leaves are known to contain antibacterial compounds, so it is necessary to find out whether fennel leaves have an effect on Methicillin-resistant Staphylococcus aureus (MRSA). This study aims to prove the antibacterial activity of ethanol extract of fennel leaves against MRSA bacteria. This study is a true experimental study to test the antibacterial activity of ethanol extract of fennel leaves against MRSA. The fennel leaves used were obtained from the slopes of Mount Bromo. MRSA bacteria were obtained from the Microbiology Laboratory of the Faculty of Medicine, Universitas Airlangga. The antibacterial test used the agar well diffusion method. SPSS version 27 was used for data analysis to perform non-parametric tests with the Kruskal–Wallis test and the Mann–Whitney post hoc test. The test results showed that the several series of ethanol extract concentrations of fennel leaves used in the test showed that a concentration of 80% formed an inhibition zone against MRSA with an average diameter of 7.12 mm. The conclusion of this study is that fennel leaf extract obtained from the slopes of Mount Bromo has the ability to inhibit the growth of MRSA. </p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_17599090
institution Zenodo
language eng
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle Antibacterial activity of fennel (Foeniculum vulgare) leaf from the slopes of Mount Bromo against Methicillin-resistant Staphylococcus aureus
Rahmah, Anindya Fatihatur
Koendhori, Eko Budi
Susanto, Joni
Antibacterial agents
Foeniculum vulgare
Ethanol Extract
MRSA
<p>Staphylococcus aureus is an infection-causing bacterium that is associated with many deaths in the world and is complicated by its adaptable condition that causes cases of antibiotic resistance. Fennel (Foeniculum vulgare) leaves are known to contain antibacterial compounds, so it is necessary to find out whether fennel leaves have an effect on Methicillin-resistant Staphylococcus aureus (MRSA). This study aims to prove the antibacterial activity of ethanol extract of fennel leaves against MRSA bacteria. This study is a true experimental study to test the antibacterial activity of ethanol extract of fennel leaves against MRSA. The fennel leaves used were obtained from the slopes of Mount Bromo. MRSA bacteria were obtained from the Microbiology Laboratory of the Faculty of Medicine, Universitas Airlangga. The antibacterial test used the agar well diffusion method. SPSS version 27 was used for data analysis to perform non-parametric tests with the Kruskal–Wallis test and the Mann–Whitney post hoc test. The test results showed that the several series of ethanol extract concentrations of fennel leaves used in the test showed that a concentration of 80% formed an inhibition zone against MRSA with an average diameter of 7.12 mm. The conclusion of this study is that fennel leaf extract obtained from the slopes of Mount Bromo has the ability to inhibit the growth of MRSA. </p>
title Antibacterial activity of fennel (Foeniculum vulgare) leaf from the slopes of Mount Bromo against Methicillin-resistant Staphylococcus aureus
topic Antibacterial agents
Foeniculum vulgare
Ethanol Extract
MRSA
url https://doi.org/10.5281/zenodo.17599090