ALPHA TOCOPHEROL AS AN ADJUVANT IN DIABETIC PATIENTS-EXTENDING BENEFITS BEYOND EXTRACTION SOCKET HEALING

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Autores principales: Dr. Pooja Sree chunduru MDS, Dr.P.S.V.P Jatin, Dr. Anu Vattikuti, Dr.Lakshmi Prasanna, Dr. N.Jyothirmai MDS, Dr. K. Radha Sindhuja MDS
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Lenguaje:inglés
Publicado: Zenodo 2025
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author Dr. Pooja Sree chunduru MDS
Dr.P.S.V.P Jatin
Dr. Anu Vattikuti
Dr.Lakshmi Prasanna
Dr. N.Jyothirmai MDS
Dr. K. Radha Sindhuja MDS
author_facet Dr. Pooja Sree chunduru MDS
Dr.P.S.V.P Jatin
Dr. Anu Vattikuti
Dr.Lakshmi Prasanna
Dr. N.Jyothirmai MDS
Dr. K. Radha Sindhuja MDS
contents <p><strong><span>ABSTRACT</span></strong></p> <p><strong><span lang="EN-US">Background:</span></strong><span>Diabetic patients often present with delayed wound healing and increased risk of post-operative complications following dental extractions due to impaired microvascular function, oxidative stress, and altered immune response. Alpha-tocopherol (Vitamin E), a potent lipid-soluble antioxidant, has been shown to reduce oxidative damage and enhance tissue repair. This study aims to evaluate the effectiveness of vitamin E as an adjunct to reduce post operative complications in extraction in diabetic Patients.</span><strong><span lang="EN-US">Materials and Methods :</span></strong><span lang="EN-US">A total of 30 patients<strong> </strong>were randomly allocated to Group E and Group S. Vitamin E was applied to Gelfoam in extraction socket in Group E, while Group S received Gelfoam with saline. Postoperative pain, incidence of dry socket were evaluated on 3<sup>rd</sup> day and healing progression were evaluated on 3<sup>rd</sup> and 7<sup>th</sup> day using standardized clinical criteria <strong>Results: </strong>Vitamin E group showed significantly reduced postoperative pain, faster healing, and lower incidence of dry socket compared to control sites and no adverse effects related to Vitamin E application were observed .<strong>Conclusion:</strong><a name="_Hlk209998390"></a> Intrasocket Vitamin E application appears to be a safe and effective adjunct for improving postoperative outcomes in diabetic patients following tooth extraction, by promoting healing, reducing pain, and minimizing the risk of dry socket.</span></p> <p><strong><span lang="EN-US">Keywords: </span></strong><span lang="EN-US">Vitamin E; Diabetic patients; extraction; Postoperative complications; Dry socket</span></p>
format Recurso digital
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language eng
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle ALPHA TOCOPHEROL AS AN ADJUVANT IN DIABETIC PATIENTS-EXTENDING BENEFITS BEYOND EXTRACTION SOCKET HEALING
Dr. Pooja Sree chunduru MDS
Dr.P.S.V.P Jatin
Dr. Anu Vattikuti
Dr.Lakshmi Prasanna
Dr. N.Jyothirmai MDS
Dr. K. Radha Sindhuja MDS
Vitamin E
Diabetic patients
extraction
Postoperative complications
Dry Socket/veterinary
<p><strong><span>ABSTRACT</span></strong></p> <p><strong><span lang="EN-US">Background:</span></strong><span>Diabetic patients often present with delayed wound healing and increased risk of post-operative complications following dental extractions due to impaired microvascular function, oxidative stress, and altered immune response. Alpha-tocopherol (Vitamin E), a potent lipid-soluble antioxidant, has been shown to reduce oxidative damage and enhance tissue repair. This study aims to evaluate the effectiveness of vitamin E as an adjunct to reduce post operative complications in extraction in diabetic Patients.</span><strong><span lang="EN-US">Materials and Methods :</span></strong><span lang="EN-US">A total of 30 patients<strong> </strong>were randomly allocated to Group E and Group S. Vitamin E was applied to Gelfoam in extraction socket in Group E, while Group S received Gelfoam with saline. Postoperative pain, incidence of dry socket were evaluated on 3<sup>rd</sup> day and healing progression were evaluated on 3<sup>rd</sup> and 7<sup>th</sup> day using standardized clinical criteria <strong>Results: </strong>Vitamin E group showed significantly reduced postoperative pain, faster healing, and lower incidence of dry socket compared to control sites and no adverse effects related to Vitamin E application were observed .<strong>Conclusion:</strong><a name="_Hlk209998390"></a> Intrasocket Vitamin E application appears to be a safe and effective adjunct for improving postoperative outcomes in diabetic patients following tooth extraction, by promoting healing, reducing pain, and minimizing the risk of dry socket.</span></p> <p><strong><span lang="EN-US">Keywords: </span></strong><span lang="EN-US">Vitamin E; Diabetic patients; extraction; Postoperative complications; Dry socket</span></p>
title ALPHA TOCOPHEROL AS AN ADJUVANT IN DIABETIC PATIENTS-EXTENDING BENEFITS BEYOND EXTRACTION SOCKET HEALING
topic Vitamin E
Diabetic patients
extraction
Postoperative complications
Dry Socket/veterinary
url https://doi.org/10.5281/zenodo.17617446