In-vitro evaluation of sun protection factor of various solvent extracts from Phragmites Australis
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2025
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| _version_ | 1866901818818166784 |
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| author | Vaishali Sharma1*, Zulphikar Ali2, Nitin Kumar3, Amit Kumar4, Bhupendra Chauhan1 |
| author_facet | Vaishali Sharma1*, Zulphikar Ali2, Nitin Kumar3, Amit Kumar4, Bhupendra Chauhan1 |
| contents | <p><span>Overexposure to ultraviolet rays is a key environmental trigger for dermal injury, premature aging, and skin cancer development. Conventional sunscreens, formulated with synthetic chemical agents, are effective in absorbing or reflecting UV rays; however, their prolonged use has been implicated with side effects such as skin irritation, hypersensitivity, and photoallergic reactions. This has prompted growing interest in natural alternatives, particularly plant-derived compounds, which offer photo-protective benefits along with additional antioxidant activity. Plants are rich sources of bioactive compounds such as phenols, flavonoids, and tannins, which are considered to scavenge free radicals and absorb UV radiation, thereby reducing reactive oxygen species and phototoxic damage. The exploration of botanical extracts as sunscreen ingredients not only addresses safety concerns but also aligns with the increasing demand for eco-friendly and biocompatible formulations. Phragmites australis (common reed), a perennial grass widely distributed across wetlands, has been traditionally recognized for its diverse pharmacological properties. Despite its abundance, limited studies have investigated its capability as a photo-protective compound. In this study, the whole plant of Phragmites australis was extracted using water, chloroform, and ethanol through cold maceration. Preliminary phytochemical screening confirmed the presence of phenols, tannins, and flavonoids in every extract. The sun protection factor (SPF) was assessed via the UV spectroscopic analysis, yielding values of 1.5338 ± 0.016 for the aqueous extract, 2.2699 ± 0.003 for the chloroform extract, and 11.025 ± 0.022 for the ethanolic extract. These findings highlight the potential of Phragmites australis extracts, particularly the ethanolic fraction, as natural sunscreen agents. Furthermore, combining extracts in optimized ratios may enhance photo-protective efficacy through synergistic or additive effects, supporting their application in the development of safe, plant-based topical formulations.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_17659012 |
| institution | Zenodo |
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| publishDate | 2025 |
| publisher | Zenodo |
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| spellingShingle | In-vitro evaluation of sun protection factor of various solvent extracts from Phragmites Australis Vaishali Sharma1*, Zulphikar Ali2, Nitin Kumar3, Amit Kumar4, Bhupendra Chauhan1 Phragmites australis, Sun protection factor, UV radiation, Mansur equation <p><span>Overexposure to ultraviolet rays is a key environmental trigger for dermal injury, premature aging, and skin cancer development. Conventional sunscreens, formulated with synthetic chemical agents, are effective in absorbing or reflecting UV rays; however, their prolonged use has been implicated with side effects such as skin irritation, hypersensitivity, and photoallergic reactions. This has prompted growing interest in natural alternatives, particularly plant-derived compounds, which offer photo-protective benefits along with additional antioxidant activity. Plants are rich sources of bioactive compounds such as phenols, flavonoids, and tannins, which are considered to scavenge free radicals and absorb UV radiation, thereby reducing reactive oxygen species and phototoxic damage. The exploration of botanical extracts as sunscreen ingredients not only addresses safety concerns but also aligns with the increasing demand for eco-friendly and biocompatible formulations. Phragmites australis (common reed), a perennial grass widely distributed across wetlands, has been traditionally recognized for its diverse pharmacological properties. Despite its abundance, limited studies have investigated its capability as a photo-protective compound. In this study, the whole plant of Phragmites australis was extracted using water, chloroform, and ethanol through cold maceration. Preliminary phytochemical screening confirmed the presence of phenols, tannins, and flavonoids in every extract. The sun protection factor (SPF) was assessed via the UV spectroscopic analysis, yielding values of 1.5338 ± 0.016 for the aqueous extract, 2.2699 ± 0.003 for the chloroform extract, and 11.025 ± 0.022 for the ethanolic extract. These findings highlight the potential of Phragmites australis extracts, particularly the ethanolic fraction, as natural sunscreen agents. Furthermore, combining extracts in optimized ratios may enhance photo-protective efficacy through synergistic or additive effects, supporting their application in the development of safe, plant-based topical formulations.</span></p> |
| title | In-vitro evaluation of sun protection factor of various solvent extracts from Phragmites Australis |
| topic | Phragmites australis, Sun protection factor, UV radiation, Mansur equation |
| url | https://doi.org/10.5281/zenodo.17659012 |