A COMPREHENSIVE REVIEW ON SODIUM ALGINATE BEADS FOR PEPTIC ULCER MANAGEMENT
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| Format: | Recurso digital |
| Langue: | anglais |
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Zenodo
2025
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| _version_ | 1866901883152498688 |
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| author | Sanjana S.*1, Ramya D.2, Shree G.2, Fathima Jamsheena N.2, Varshitha D.2, Shivubairegowda U. N.2 |
| author_facet | Sanjana S.*1, Ramya D.2, Shree G.2, Fathima Jamsheena N.2, Varshitha D.2, Shivubairegowda U. N.2 |
| contents | <p>Peptic<span> </span>ulcer disease (PUD)<span> </span>is a prevalent gastrointestinal disorder characterized by mucosal injury due to excessive gastric acid and pepsin secretion. Affecting approximately 10% of the global population, PUD is a chronic condition with significant morbidity. Helicobacter pylori (H. pylori) infection and nonsteroidal<span> </span>anti-inflammatory<span> </span>drugs<span> </span>(NSAIDs)<span> </span>are<span> </span>the<span> </span>primary<span> </span>causes<span> </span>of<span> </span>PUD.<span> </span>However,<span> </span><span>eradicating </span>H. pylori infections poses significant challenges, including poor drug accessibility and short gastric residence times. Sodium alginate beads have emerged as a promising drug delivery system, offering regulated release and improved bioavailability. This review provides a comprehensive overview of recent advancements in sodium alginate bead formulation and evaluation methodologies. The integration of innovative formulation strategies and precise evaluation techniques has significantly enhanced the<span> </span>performance<span> </span>and functionality of<span> </span>sodium alginate<span> </span>beads, paving the<span> </span>way for<span> </span>their<span> </span>diverse applications in drug delivery and tissue engineering.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_17747243 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | A COMPREHENSIVE REVIEW ON SODIUM ALGINATE BEADS FOR PEPTIC ULCER MANAGEMENT Sanjana S.*1, Ramya D.2, Shree G.2, Fathima Jamsheena N.2, Varshitha D.2, Shivubairegowda U. N.2 <p>Peptic<span> </span>ulcer disease (PUD)<span> </span>is a prevalent gastrointestinal disorder characterized by mucosal injury due to excessive gastric acid and pepsin secretion. Affecting approximately 10% of the global population, PUD is a chronic condition with significant morbidity. Helicobacter pylori (H. pylori) infection and nonsteroidal<span> </span>anti-inflammatory<span> </span>drugs<span> </span>(NSAIDs)<span> </span>are<span> </span>the<span> </span>primary<span> </span>causes<span> </span>of<span> </span>PUD.<span> </span>However,<span> </span><span>eradicating </span>H. pylori infections poses significant challenges, including poor drug accessibility and short gastric residence times. Sodium alginate beads have emerged as a promising drug delivery system, offering regulated release and improved bioavailability. This review provides a comprehensive overview of recent advancements in sodium alginate bead formulation and evaluation methodologies. The integration of innovative formulation strategies and precise evaluation techniques has significantly enhanced the<span> </span>performance<span> </span>and functionality of<span> </span>sodium alginate<span> </span>beads, paving the<span> </span>way for<span> </span>their<span> </span>diverse applications in drug delivery and tissue engineering.</p> |
| title | A COMPREHENSIVE REVIEW ON SODIUM ALGINATE BEADS FOR PEPTIC ULCER MANAGEMENT |
| url | https://doi.org/10.5281/zenodo.17747243 |