Guardado en:
| Autor principal: | |
|---|---|
| Formato: | Recurso digital |
| Lenguaje: | |
| Publicado: |
Zenodo
2025
|
| Acceso en línea: | https://doi.org/10.5281/zenodo.17878865 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1866901496459689984 |
|---|---|
| author | Dr. Shahid Mohammed*2, Md. Aamir Hussain*1, Nazia Mahveen Khan*3 |
| author_facet | Dr. Shahid Mohammed*2, Md. Aamir Hussain*1, Nazia Mahveen Khan*3 |
| contents | <p><span>This study successfully developed bilayer tablets combining azithromycin (IR layer) for rapid and levofloxacin (SR layer) for rapid for prolonged release. Slugging technique and super disintegrants helped azithromycin's faster dissolution. Different grades of HPMC helped prolonged the release of Levofloxacin for up to 12 hours. Optimized bilayer tablet demonstrated good physical properties, rapid solubilization<span> </span>of azithromycin, and sustained release of levofloxacin.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_17878865 |
| institution | Zenodo |
| language | |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | DESIGN, CHARACTERIZATION AND IN-VITRO EVALUATION OF A NOVEL BILAYERTABLET COMBINING IMMEDIATE-RELEASE AZITHROMYCIN(WITHSUPERDISINTEGRANT VIA SLUGGING METHOD ) AND SUSTAINED-RELEASE LEVOFLOXACIN(WITH HYPROMELLOSE VIA DIRECT COMPRESSION) FORSEQUENTIAL ANTIBIOTIC THERAPY Dr. Shahid Mohammed*2, Md. Aamir Hussain*1, Nazia Mahveen Khan*3 <p><span>This study successfully developed bilayer tablets combining azithromycin (IR layer) for rapid and levofloxacin (SR layer) for rapid for prolonged release. Slugging technique and super disintegrants helped azithromycin's faster dissolution. Different grades of HPMC helped prolonged the release of Levofloxacin for up to 12 hours. Optimized bilayer tablet demonstrated good physical properties, rapid solubilization<span> </span>of azithromycin, and sustained release of levofloxacin.</span></p> |
| title | DESIGN, CHARACTERIZATION AND IN-VITRO EVALUATION OF A NOVEL BILAYERTABLET COMBINING IMMEDIATE-RELEASE AZITHROMYCIN(WITHSUPERDISINTEGRANT VIA SLUGGING METHOD ) AND SUSTAINED-RELEASE LEVOFLOXACIN(WITH HYPROMELLOSE VIA DIRECT COMPRESSION) FORSEQUENTIAL ANTIBIOTIC THERAPY |
| url | https://doi.org/10.5281/zenodo.17878865 |