| _version_ | 1866901726290771968 |
|---|---|
| author | Bedeir, Ruwan La Piana, Roberta Hassan, Aleyeldin |
| author_facet | Bedeir, Ruwan La Piana, Roberta Hassan, Aleyeldin |
| contents | <p>By definition, all HSP patients present clinically with spastic paraparesis; to narrow down the differential diagnoses among HSPs and HSP mimickers (e.g. multiple sclerosis), prompt correct recognition of key radiological features becomes critical. Among<br>imaging findings associated with HSP, the involvement of white matter structures and tracts are particularly relevant. This software is an imaging-based algorithm of common MRI features associated with HSPs, to be used by radiologists, clinicians, trainees, and patients and caregivers to narrow down their differential diagnosis, find and review scientific articles, and find educative material on HSPs with white matter abnormalities.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_17930370 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Imaging-based diagnostic algorithm for HSPs with associated white matter abnormalities Bedeir, Ruwan La Piana, Roberta Hassan, Aleyeldin hereditary spastic paraplegia Spastic Paraplegia, Hereditary Spastic Paraplegia, Hereditary/diagnosis Leukodystrophy MRI features Imaging biomarkers <p>By definition, all HSP patients present clinically with spastic paraparesis; to narrow down the differential diagnoses among HSPs and HSP mimickers (e.g. multiple sclerosis), prompt correct recognition of key radiological features becomes critical. Among<br>imaging findings associated with HSP, the involvement of white matter structures and tracts are particularly relevant. This software is an imaging-based algorithm of common MRI features associated with HSPs, to be used by radiologists, clinicians, trainees, and patients and caregivers to narrow down their differential diagnosis, find and review scientific articles, and find educative material on HSPs with white matter abnormalities.</p> |
| title | Imaging-based diagnostic algorithm for HSPs with associated white matter abnormalities |
| topic | hereditary spastic paraplegia Spastic Paraplegia, Hereditary Spastic Paraplegia, Hereditary/diagnosis Leukodystrophy MRI features Imaging biomarkers |
| url | https://doi.org/10.5281/zenodo.17930370 |