Systematic Literature Review of Abutilon indicum: Pharmacognosy, Phytochemistry, and Reported Bioactivities
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2025
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| author | Sareesh Kankanaka, Pavani Nikshipta, Poloju Mukesh, Mir Saad Akram, N. Bhargavi |
| author_facet | Sareesh Kankanaka, Pavani Nikshipta, Poloju Mukesh, Mir Saad Akram, N. Bhargavi |
| contents | <p><span>Abutilon indicum (L.), commonly known as “Atibala,” is a perennial shrub belonging to the Malvaceae family and is widely distributed in tropical and subtropical regions. Traditionally, it has been used in Ayurvedic, Siddha, and Unani medicine for the treatment of various ailments, including inflammation, respiratory disorders, diabetes, liver disorders, and urinary complaints. The plant contains diverse phytochemicals such as flavonoids, alkaloids, tannins, saponins, glycosides, phenolics, steroids, and essential oils, which are responsible for its broad spectrum of biological activities. Pharmacological studies have demonstrated anti-inflammatory, analgesic, hepatoprotective, antioxidant, hypoglycemic, immunomodulatory, antimicrobial, anti-arthritic, anti-cancer, and wound healing activities, validating many of its traditional uses. Standardization of extracts using chemical markers like luteolin and evaluation of physicochemical parameters enhance the quality control and reproducibility of its therapeutic effects. Despite extensive in vitro and in vivo studies, clinical investigations remain limited, and comprehensive toxicological evaluations are scarce. Research gaps include the need for standardized extraction procedures, detailed molecular mechanism studies, and well-designed clinical trials to confirm efficacy and safety in humans. Future perspectives focus on isolating novel bioactive compounds, elucidating their pharmacodynamic mechanisms, and developing standardized herbal formulations. Overall, Abutilon indicum represents a valuable medicinal plant with significant pharmacological potential and wide-ranging therapeutic applications, making it a promising candidate for future drug discovery and herbal product development.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_18045478 |
| institution | Zenodo |
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| publishDate | 2025 |
| publisher | Zenodo |
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| spellingShingle | Systematic Literature Review of Abutilon indicum: Pharmacognosy, Phytochemistry, and Reported Bioactivities Sareesh Kankanaka, Pavani Nikshipta, Poloju Mukesh, Mir Saad Akram, N. Bhargavi Abutilon indicum, Phytochemicals, Pharmacological activities, Traditional medicine, Bioactive compounds <p><span>Abutilon indicum (L.), commonly known as “Atibala,” is a perennial shrub belonging to the Malvaceae family and is widely distributed in tropical and subtropical regions. Traditionally, it has been used in Ayurvedic, Siddha, and Unani medicine for the treatment of various ailments, including inflammation, respiratory disorders, diabetes, liver disorders, and urinary complaints. The plant contains diverse phytochemicals such as flavonoids, alkaloids, tannins, saponins, glycosides, phenolics, steroids, and essential oils, which are responsible for its broad spectrum of biological activities. Pharmacological studies have demonstrated anti-inflammatory, analgesic, hepatoprotective, antioxidant, hypoglycemic, immunomodulatory, antimicrobial, anti-arthritic, anti-cancer, and wound healing activities, validating many of its traditional uses. Standardization of extracts using chemical markers like luteolin and evaluation of physicochemical parameters enhance the quality control and reproducibility of its therapeutic effects. Despite extensive in vitro and in vivo studies, clinical investigations remain limited, and comprehensive toxicological evaluations are scarce. Research gaps include the need for standardized extraction procedures, detailed molecular mechanism studies, and well-designed clinical trials to confirm efficacy and safety in humans. Future perspectives focus on isolating novel bioactive compounds, elucidating their pharmacodynamic mechanisms, and developing standardized herbal formulations. Overall, Abutilon indicum represents a valuable medicinal plant with significant pharmacological potential and wide-ranging therapeutic applications, making it a promising candidate for future drug discovery and herbal product development.</span></p> |
| title | Systematic Literature Review of Abutilon indicum: Pharmacognosy, Phytochemistry, and Reported Bioactivities |
| topic | Abutilon indicum, Phytochemicals, Pharmacological activities, Traditional medicine, Bioactive compounds |
| url | https://doi.org/10.5281/zenodo.18045478 |