Down Syndrome: A Case Report with Concise Review

Fuente: Zenodo
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Autor principal: People's University
Formato: Recurso digital
Lenguaje:inglés
Publicado: Zenodo 2025
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author People's University
author_facet People's University
contents <p>Down Syndrome is a common disorder with phenotypes including leukemia, congenital heart defects <br>and Alzheimers disease. It is a chromosomal abnormality which leads to mild to moderate intellectual <br>ailment and this impairment causes dysfunctioning of multiple organs including the orofacial region. <br>The extra genetic material can result in disturbed mental and physical growth of the child. Mental <br>retardation, delayed language and motor development, delay in fetal brain growth, prenatal and postnatal <br>growth  deficiency,  gastrointestinal  malformations,  congenital  hematologic  disorders,  and  cardiac <br>abnormalities are observed in this disorder. Dental and craniofacial features include brachycephaly, flat <br>occiput, mandibular prognathism and reduction in parotid salivary flow rate. Necrotizing ulcerative <br>gingivitis, periodontal disease and delay in eruption of both deciduous and permanent teeth is observed <br>in this disorder. This article aims to discuss the clinical features and management of a six year old male <br>child showing classical signs of this disorder.</p>
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publishDate 2025
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spellingShingle Down Syndrome: A Case Report with Concise Review
People's University
Down's syndrome, disorder, growth, deficiency
<p>Down Syndrome is a common disorder with phenotypes including leukemia, congenital heart defects <br>and Alzheimers disease. It is a chromosomal abnormality which leads to mild to moderate intellectual <br>ailment and this impairment causes dysfunctioning of multiple organs including the orofacial region. <br>The extra genetic material can result in disturbed mental and physical growth of the child. Mental <br>retardation, delayed language and motor development, delay in fetal brain growth, prenatal and postnatal <br>growth  deficiency,  gastrointestinal  malformations,  congenital  hematologic  disorders,  and  cardiac <br>abnormalities are observed in this disorder. Dental and craniofacial features include brachycephaly, flat <br>occiput, mandibular prognathism and reduction in parotid salivary flow rate. Necrotizing ulcerative <br>gingivitis, periodontal disease and delay in eruption of both deciduous and permanent teeth is observed <br>in this disorder. This article aims to discuss the clinical features and management of a six year old male <br>child showing classical signs of this disorder.</p>
title Down Syndrome: A Case Report with Concise Review
topic Down's syndrome, disorder, growth, deficiency
url https://doi.org/10.5281/zenodo.18065975