Langerhans Cell Histiocytosis Masquerading as Hodgkin Lymphoma

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Main Author: International Journal of Medical Science and Advanced Clinical Research (IJMACR)
Format: Recurso digital
Language:English
Published: Zenodo 2025
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author International Journal of Medical Science and Advanced Clinical Research (IJMACR)
author_facet International Journal of Medical Science and Advanced Clinical Research (IJMACR)
contents <p><strong><span lang="EN-IN">Abstract</span></strong></p> <p><span>Langerhans cell histiocytosis (LCH) is a rare clonal proliferative disorder characterized by the accumulation of abnormal Langerhans-type dendritic cells<sup>1</sup>. Although it is classified as a neoplasm, it exhibits a wide spectrum of clinical presentations, ranging from isolated lesions to disseminated, multisystem involvement. LCH primarily affects the paediatric population, with the majority of cases diagnosed in children under the age of 10. However, occurrences in adults, though less frequent, have also been documented. Recent research indicates that LCH arises from myeloid precursor dendritic cells, reinforcing its characterization as a neoplastic disorder rather than a solely reactive process.<sup>2</sup></span></p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_18277930
institution Zenodo
language eng
publishDate 2025
publisher Zenodo
record_format zenodo
spellingShingle Langerhans Cell Histiocytosis Masquerading as Hodgkin Lymphoma
International Journal of Medical Science and Advanced Clinical Research (IJMACR)
sinus histiocytosis with massive lymphadenopathy
<p><strong><span lang="EN-IN">Abstract</span></strong></p> <p><span>Langerhans cell histiocytosis (LCH) is a rare clonal proliferative disorder characterized by the accumulation of abnormal Langerhans-type dendritic cells<sup>1</sup>. Although it is classified as a neoplasm, it exhibits a wide spectrum of clinical presentations, ranging from isolated lesions to disseminated, multisystem involvement. LCH primarily affects the paediatric population, with the majority of cases diagnosed in children under the age of 10. However, occurrences in adults, though less frequent, have also been documented. Recent research indicates that LCH arises from myeloid precursor dendritic cells, reinforcing its characterization as a neoplastic disorder rather than a solely reactive process.<sup>2</sup></span></p>
title Langerhans Cell Histiocytosis Masquerading as Hodgkin Lymphoma
topic sinus histiocytosis with massive lymphadenopathy
url https://doi.org/10.5281/zenodo.18277930