CLINICAL OUTCOMES OF AMBROXOL HYDROCHLORIDE IN INFANTS WITH SECRETORY OTITIS MEDIA
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| Natura: | Recurso digital |
| Lingua: | inglese |
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Zenodo
2025
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| _version_ | 1866901632706412544 |
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| author | Liwen, Chen, MD, PhD Minghao, Jun Zhang, MD |
| author_facet | Liwen, Chen, MD, PhD Minghao, Jun Zhang, MD |
| contents | <p><span>This study evaluates the clinical efficacy of ambroxol hydrochloride in treating infantile secretory otitis media (SOM). Ninety-two infants diagnosed with SOM were randomly divided into an experimental group receiving conventional treatment plus ambroxol hydrochloride, and a control group receiving routine care alone. Treatment effectiveness, inflammatory markers (SIL-2R and IL-8), pure tone threshold air-bone gap, tympanic pressure, and adverse reactions were compared. The experimental group demonstrated a significantly higher treatment effectiveness rate (P<0.05), increased SIL-2R and IL-8 levels (P<0.05), reduced air-bone gap (P<0.05), improved tympanic pressure (P<0.05), and lower incidence of adverse reactions (P<0.05) compared to controls. These results indicate that ambroxol hydrochloride enhances clinical outcomes and safety in infant SOM treatment, supporting its valuable application in clinical nursing.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_18399455 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | CLINICAL OUTCOMES OF AMBROXOL HYDROCHLORIDE IN INFANTS WITH SECRETORY OTITIS MEDIA Liwen, Chen, MD, PhD Minghao, Jun Zhang, MD Ambroxol hydrochloride; Secretory otitis media; Clinical efficacy; pure tone threshold <p><span>This study evaluates the clinical efficacy of ambroxol hydrochloride in treating infantile secretory otitis media (SOM). Ninety-two infants diagnosed with SOM were randomly divided into an experimental group receiving conventional treatment plus ambroxol hydrochloride, and a control group receiving routine care alone. Treatment effectiveness, inflammatory markers (SIL-2R and IL-8), pure tone threshold air-bone gap, tympanic pressure, and adverse reactions were compared. The experimental group demonstrated a significantly higher treatment effectiveness rate (P<0.05), increased SIL-2R and IL-8 levels (P<0.05), reduced air-bone gap (P<0.05), improved tympanic pressure (P<0.05), and lower incidence of adverse reactions (P<0.05) compared to controls. These results indicate that ambroxol hydrochloride enhances clinical outcomes and safety in infant SOM treatment, supporting its valuable application in clinical nursing.</span></p> |
| title | CLINICAL OUTCOMES OF AMBROXOL HYDROCHLORIDE IN INFANTS WITH SECRETORY OTITIS MEDIA |
| topic | Ambroxol hydrochloride; Secretory otitis media; Clinical efficacy; pure tone threshold |
| url | https://doi.org/10.5281/zenodo.18399455 |