Interpretable Machine Learning of Nonlinear EEG Dynamics Enables Robust Differentiation of Alzheimer's Disease and Frontotemporal Dementia

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Autori principali: Salehi, Arman, Heydarian, Ashkan, Milani, Dornaz, Mortazavy Beni, Hamidreza, Kheirandish, parsa
Natura: Recurso digital
Pubblicazione: Zenodo 2026
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author Salehi, Arman
Heydarian, Ashkan
Milani, Dornaz
Mortazavy Beni, Hamidreza
Kheirandish, parsa
author_facet Salehi, Arman
Heydarian, Ashkan
Milani, Dornaz
Mortazavy Beni, Hamidreza
Kheirandish, parsa
contents <p>This repository contains the complete computational pipeline for the study titled <strong>“Interpretable EEG-based classification of Alzheimer’s disease and frontotemporal dementia using nonlinear dynamics and explainable machine learning.”</strong> The project develops and validates a transparent machine learning framework to distinguish Alzheimer’s disease (AD), behavioral variant frontotemporal dementia (FTD), and healthy controls (HC) using resting-state electroencephalography (EEG). The methodology emphasizes <strong>nonlinear dynamic features</strong> (e.g., recurrence quantification, Lyapunov exponents, multiscale entropy) and <strong>model interpretability</strong> via SHAP and topographic mapping.</p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_18496634
institution Zenodo
language
publishDate 2026
publisher Zenodo
record_format zenodo
spellingShingle Interpretable Machine Learning of Nonlinear EEG Dynamics Enables Robust Differentiation of Alzheimer's Disease and Frontotemporal Dementia
Salehi, Arman
Heydarian, Ashkan
Milani, Dornaz
Mortazavy Beni, Hamidreza
Kheirandish, parsa
<p>This repository contains the complete computational pipeline for the study titled <strong>“Interpretable EEG-based classification of Alzheimer’s disease and frontotemporal dementia using nonlinear dynamics and explainable machine learning.”</strong> The project develops and validates a transparent machine learning framework to distinguish Alzheimer’s disease (AD), behavioral variant frontotemporal dementia (FTD), and healthy controls (HC) using resting-state electroencephalography (EEG). The methodology emphasizes <strong>nonlinear dynamic features</strong> (e.g., recurrence quantification, Lyapunov exponents, multiscale entropy) and <strong>model interpretability</strong> via SHAP and topographic mapping.</p>
title Interpretable Machine Learning of Nonlinear EEG Dynamics Enables Robust Differentiation of Alzheimer's Disease and Frontotemporal Dementia
url https://doi.org/10.5281/zenodo.18496634