Genetics of Polymorphism in Nitrogen-Induced-Susceptibility (NIS) of Rice to Magnaporthe oryzae

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Main Authors: Yanfang, Liu, Md. Hasibur Rahaman, Hera, Owais, Iqba, Sauban Musa, Jibril, Yi, Yi, Chengyun, Li
Format: Recurso digital
Language:English
Published: Zenodo 2026
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author Yanfang, Liu
Md. Hasibur Rahaman, Hera
Owais, Iqba
Sauban Musa, Jibril
Yi, Yi
Chengyun, Li
author_facet Yanfang, Liu
Md. Hasibur Rahaman, Hera
Owais, Iqba
Sauban Musa, Jibril
Yi, Yi
Chengyun, Li
contents <p><span>Nitrogen fertilization is essential for crop yield but can increase susceptibility to rice blast<strong>,</strong> a phenomenon known as Nitrogen-Induced Susceptibility (NIS). The genetic architecture governing natural variation in NIS remains poorly characterized. To address this, we performed a genome-wide association study (GWAS) using a diverse panel of 268 rice accessions from the rice diversity panel 2, under controlled nitrogen regimes 0N (control),1N (</span><span>100 mg/L NH₄NO₃</span><span>), 2N (</span><span>200 mg/L NH₄NO₃</span><span>). Our analyses defined a NIS Index (NISI), which revealed extensive polymorphism. GWAS identified several significant loci, including a novel locus on chromosome 8 (NIS4) harboring F-box protein genes. Physiological dissection showed that a 'negative NIS' phenotype (enhanced resistance under high nitrogen) correlated with a rapid, pathogen-triggered defense response, characterized by immediate induction of peroxidase activity and lignin biosynthesis. Conversely, susceptible lines exhibited delayed defense. Gene expression analysis linked active nitrogen assimilation (GS/GOGAT cycle) to susceptibility. We conclude that NIS polymorphism is genetically controlled and hinges on the host's ability to redirect nitrogen resources toward early defense activation during pathogen invasion.</span></p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_18629189
institution Zenodo
language eng
publishDate 2026
publisher Zenodo
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spellingShingle Genetics of Polymorphism in Nitrogen-Induced-Susceptibility (NIS) of Rice to Magnaporthe oryzae
Yanfang, Liu
Md. Hasibur Rahaman, Hera
Owais, Iqba
Sauban Musa, Jibril
Yi, Yi
Chengyun, Li
nitrogen-induced susceptibility (NIS), rice blast, GWAS, polymorphism, peroxidase, lignin, F-box protein
<p><span>Nitrogen fertilization is essential for crop yield but can increase susceptibility to rice blast<strong>,</strong> a phenomenon known as Nitrogen-Induced Susceptibility (NIS). The genetic architecture governing natural variation in NIS remains poorly characterized. To address this, we performed a genome-wide association study (GWAS) using a diverse panel of 268 rice accessions from the rice diversity panel 2, under controlled nitrogen regimes 0N (control),1N (</span><span>100 mg/L NH₄NO₃</span><span>), 2N (</span><span>200 mg/L NH₄NO₃</span><span>). Our analyses defined a NIS Index (NISI), which revealed extensive polymorphism. GWAS identified several significant loci, including a novel locus on chromosome 8 (NIS4) harboring F-box protein genes. Physiological dissection showed that a 'negative NIS' phenotype (enhanced resistance under high nitrogen) correlated with a rapid, pathogen-triggered defense response, characterized by immediate induction of peroxidase activity and lignin biosynthesis. Conversely, susceptible lines exhibited delayed defense. Gene expression analysis linked active nitrogen assimilation (GS/GOGAT cycle) to susceptibility. We conclude that NIS polymorphism is genetically controlled and hinges on the host's ability to redirect nitrogen resources toward early defense activation during pathogen invasion.</span></p>
title Genetics of Polymorphism in Nitrogen-Induced-Susceptibility (NIS) of Rice to Magnaporthe oryzae
topic nitrogen-induced susceptibility (NIS), rice blast, GWAS, polymorphism, peroxidase, lignin, F-box protein
url https://doi.org/10.5281/zenodo.18629189