Transition metal triflates catalyzed Synthesis of 1-(2-methyl-1, 5- diphenyl-1H-pyrrol-3-yl) ethanone Analogous and Study of Their Antimicrobial activity
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2026
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| _version_ | 1866901206370091008 |
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| author | SrideviKhadgamalaN Dr.AnjumAara Dr.K.Prathap B.V.Durgarao Dr.N.Krishnarao |
| author_facet | SrideviKhadgamalaN Dr.AnjumAara Dr.K.Prathap B.V.Durgarao Dr.N.Krishnarao |
| contents | <p><span>The investigation of new class antibacterial agent of a series 1-(2-methyl-1,5-diphenyl-1Hpyrrol-3-yl)ethanone derivatives (4a–4i) were success fully prepared from phenacyl bromide ,<br>substituted aromatic amine and Aetylacetone in the presence of transition metal triflates such as<br>Cu(OTf)</span><span>2 </span><span>employed in ethanol under at 70</span><span>0</span><span>C. The designed compounds were examined by advanced<br>spectroscopic data such as </span><span>1</span><span>HNMR, </span><span>13</span><span>CNMR and LCMS and elemental analysis. The protocol has<br>been used because of its excellent yield, short reaction time, mild reaction conditions, and<br>straightforward workup process. 84–92% yields of the synthetic derivatives were obtained. In<br>additionally newly synthesized derivatives were evaluated for their antibacterial activity.</span> </p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_18721689 |
| institution | Zenodo |
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| publishDate | 2026 |
| publisher | Zenodo |
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| spellingShingle | Transition metal triflates catalyzed Synthesis of 1-(2-methyl-1, 5- diphenyl-1H-pyrrol-3-yl) ethanone Analogous and Study of Their Antimicrobial activity SrideviKhadgamalaN Dr.AnjumAara Dr.K.Prathap B.V.Durgarao Dr.N.Krishnarao <p><span>The investigation of new class antibacterial agent of a series 1-(2-methyl-1,5-diphenyl-1Hpyrrol-3-yl)ethanone derivatives (4a–4i) were success fully prepared from phenacyl bromide ,<br>substituted aromatic amine and Aetylacetone in the presence of transition metal triflates such as<br>Cu(OTf)</span><span>2 </span><span>employed in ethanol under at 70</span><span>0</span><span>C. The designed compounds were examined by advanced<br>spectroscopic data such as </span><span>1</span><span>HNMR, </span><span>13</span><span>CNMR and LCMS and elemental analysis. The protocol has<br>been used because of its excellent yield, short reaction time, mild reaction conditions, and<br>straightforward workup process. 84–92% yields of the synthetic derivatives were obtained. In<br>additionally newly synthesized derivatives were evaluated for their antibacterial activity.</span> </p> |
| title | Transition metal triflates catalyzed Synthesis of 1-(2-methyl-1, 5- diphenyl-1H-pyrrol-3-yl) ethanone Analogous and Study of Their Antimicrobial activity |
| url | https://doi.org/10.5281/zenodo.18721689 |