Formulation and Evaluation of Green Synthesis of Copper Nanoparticles from Neem and Coconut

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1. Verfasser: Abhishek Singh*, Harsha Sonaye
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Veröffentlicht: Zenodo 2026
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author Abhishek Singh*, Harsha Sonaye
author_facet Abhishek Singh*, Harsha Sonaye
contents <p><span lang="EN-US">Green synthesis has been proposed as a more sustainable and environmentally green method of producing metal nanoparticles, which does not require the application of dangerous chemicals and high-energy sources. The current review deals with the purchase of copper nanoparticles (CuNPs) and copper oxide nanoparticles (CuONPs) using neem (Azadirachta indica) leaf extract and copse nut (Cocos nucifera) copra extract or husk extract. As the literature in 2021-2025 indicates, these nanoparticles are mostly spherical and have a diameter of 1060 nm and are also well-stable in aqueous conditions. Their antimicrobial activity is illustrated to be powerful on most popular pathogens including Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa with zones of inhibition of 15 to 28 mm and minimum inhibitory concentration (MIC) of 20-125 ug/M. The nanoparticles have also been found to favor wound healing through the reduction of inflammation and cell proliferation as well as they are not highly cytotoxic to human cells. Neem polyphenols, flavonoids as well as coconut lauric acid are significant reducing/stabilizing agents. It has a great potential in application in antimicrobial cream, wound dressing and topical delivering drug systems using these green CuNPs. Simple laboratory protocols that are appropriate among undergraduate pharmacy learners are identified in the review too, and prospects in sustainable pharmaceutical nanotechnology discussed.</span></p>
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spellingShingle Formulation and Evaluation of Green Synthesis of Copper Nanoparticles from Neem and Coconut
Abhishek Singh*, Harsha Sonaye
Green synthesis, Copper nanoparticles, Copper oxide nanoparticles, Neem extract, Coconut extract, Antimicrobial activity, Wound healing, Sustainable nanotechnology, Phytochemicals, Drug delivery systems.
<p><span lang="EN-US">Green synthesis has been proposed as a more sustainable and environmentally green method of producing metal nanoparticles, which does not require the application of dangerous chemicals and high-energy sources. The current review deals with the purchase of copper nanoparticles (CuNPs) and copper oxide nanoparticles (CuONPs) using neem (Azadirachta indica) leaf extract and copse nut (Cocos nucifera) copra extract or husk extract. As the literature in 2021-2025 indicates, these nanoparticles are mostly spherical and have a diameter of 1060 nm and are also well-stable in aqueous conditions. Their antimicrobial activity is illustrated to be powerful on most popular pathogens including Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa with zones of inhibition of 15 to 28 mm and minimum inhibitory concentration (MIC) of 20-125 ug/M. The nanoparticles have also been found to favor wound healing through the reduction of inflammation and cell proliferation as well as they are not highly cytotoxic to human cells. Neem polyphenols, flavonoids as well as coconut lauric acid are significant reducing/stabilizing agents. It has a great potential in application in antimicrobial cream, wound dressing and topical delivering drug systems using these green CuNPs. Simple laboratory protocols that are appropriate among undergraduate pharmacy learners are identified in the review too, and prospects in sustainable pharmaceutical nanotechnology discussed.</span></p>
title Formulation and Evaluation of Green Synthesis of Copper Nanoparticles from Neem and Coconut
topic Green synthesis, Copper nanoparticles, Copper oxide nanoparticles, Neem extract, Coconut extract, Antimicrobial activity, Wound healing, Sustainable nanotechnology, Phytochemicals, Drug delivery systems.
url https://doi.org/10.5281/zenodo.18749592