HAEMATOLOGY/ONCOLOGY ICU OUTCOMES AT THE CANBERRA HOSPITAL: A RETROSPECTIVE COHORT STUDY
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| Natura: | Recurso digital |
| Lingua: | inglese |
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2025
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| _version_ | 1866901352055046144 |
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| author | Reynolds, Samuel Mark |
| author_facet | Reynolds, Samuel Mark |
| contents | <p>Background: Outcomes for hematology/oncology patients have improved, however determining their suitability for ICU admission remains challenging and controversial. <br>Aim: Examine outcomes of patients admitted to an Australian tertiary hospital Intensive Care Unit <br>(ICU) and explore potential prognostic factors. <br>Methods: A retrospective review of patients with hematological and solid tumour malignancies no electively admitted to The Canberra Hospital (TCH) ICU, between January 2008 and <br>December 2012. Patient demographics, cancer details, reasons for ICU admission and APACHE II scores were collected and survival rates calculated and correlated with potential prognostic factors. <br>Results: Of 205 patients, 113 (55%) had hematological malignancies, and 92 (45%) solid tumours; 58% male, and mean age 60.3 years (SD 13.4). 82% of solid tumour patients had metastatic disease and 55% received palliative chemotherapy. Primary reasons for ICU admission included sepsis (59%), respiratory distress (37%) and hypotension/shock (18%). Mean APACHE II score was 20.1(SD 0.55); mean length of stay in ICU, 4 days (SD 5.2); ICU survival was 76% with 62% and 41% alive at 30-days and 6 months respectively. Overall 1 year survival was 36%. High APACHE II scores and ≥2 organs failing were significant risk factors for 30-day mortality. <br>Conclusion: Short-term outcomes were similar to contemporary studies from a general tertiary hospital setting and better than historical data. 62% of patients were alive 30 days post-ICU admission, with a significant minority alive at 12 months, confirming some patients achieved worthwhile outcomes. Further research is needed to ensure appropriate patient selection and to explore quality of life post ICU. </p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_18847727 |
| institution | Zenodo |
| language | eng |
| publishDate | 2025 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | HAEMATOLOGY/ONCOLOGY ICU OUTCOMES AT THE CANBERRA HOSPITAL: A RETROSPECTIVE COHORT STUDY Reynolds, Samuel Mark Intensive care unit, oncology, outcomes, prognosis, hematology Background <p>Background: Outcomes for hematology/oncology patients have improved, however determining their suitability for ICU admission remains challenging and controversial. <br>Aim: Examine outcomes of patients admitted to an Australian tertiary hospital Intensive Care Unit <br>(ICU) and explore potential prognostic factors. <br>Methods: A retrospective review of patients with hematological and solid tumour malignancies no electively admitted to The Canberra Hospital (TCH) ICU, between January 2008 and <br>December 2012. Patient demographics, cancer details, reasons for ICU admission and APACHE II scores were collected and survival rates calculated and correlated with potential prognostic factors. <br>Results: Of 205 patients, 113 (55%) had hematological malignancies, and 92 (45%) solid tumours; 58% male, and mean age 60.3 years (SD 13.4). 82% of solid tumour patients had metastatic disease and 55% received palliative chemotherapy. Primary reasons for ICU admission included sepsis (59%), respiratory distress (37%) and hypotension/shock (18%). Mean APACHE II score was 20.1(SD 0.55); mean length of stay in ICU, 4 days (SD 5.2); ICU survival was 76% with 62% and 41% alive at 30-days and 6 months respectively. Overall 1 year survival was 36%. High APACHE II scores and ≥2 organs failing were significant risk factors for 30-day mortality. <br>Conclusion: Short-term outcomes were similar to contemporary studies from a general tertiary hospital setting and better than historical data. 62% of patients were alive 30 days post-ICU admission, with a significant minority alive at 12 months, confirming some patients achieved worthwhile outcomes. Further research is needed to ensure appropriate patient selection and to explore quality of life post ICU. </p> |
| title | HAEMATOLOGY/ONCOLOGY ICU OUTCOMES AT THE CANBERRA HOSPITAL: A RETROSPECTIVE COHORT STUDY |
| topic | Intensive care unit, oncology, outcomes, prognosis, hematology Background |
| url | https://doi.org/10.5281/zenodo.18847727 |