DRUG-INDUCED THROMBOCYTOPENIA IN PSYCHIATRIC PATIENTS: EARLY RECOGNITION AND CASE-BASED MULTIDISCIPLINARY MANAGEMENT

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Autore principale: Laleh, Zand Reza
Natura: Recurso digital
Lingua:inglese
Pubblicazione: Zenodo 2026
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author Laleh, Zand Reza
author_facet Laleh, Zand Reza
contents <p>Background and Aim: Drug-induced thrombocytopenia (DIT) is a rare but potentially life-threatening condition triggered by certain medications. This report aims to emphasize the importance of early diagnosis and appropriate management of DIT in patients with Major Depressive Disorder (MDD) treated with a polypharmacy regimen. <br>Case Presentation: A case study of a 39-year-old woman with MDD who developed bleeding following treatment with “aripiprazole”, “olanzapine”, “lorazepam”, and “sodium valproate” is presented.  <br>Conclusion: The patient’s condition improved significantly after medication changes and close collaboration between psychiatrists and hematologists. This highlights the need for proper care and correct prescription of medicines for patients with MDD. <br>Laboratory Highlights & Technical Implications: This case report demonstrates the need for: <br>•    Enhanced CBC review protocols for patients receiving psychiatric care/treatment who are on polypharmacy; •     Reflex testing algorithms for thrombocytopenia (low platelet count) workups; <br>•    Standardized communication channels between lab and mental health teams. </p>
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spellingShingle DRUG-INDUCED THROMBOCYTOPENIA IN PSYCHIATRIC PATIENTS: EARLY RECOGNITION AND CASE-BASED MULTIDISCIPLINARY MANAGEMENT
Laleh, Zand Reza
Drug-Induced Thrombocytopenia; Platelet; Major Depressive Disorder (MDD); CBC Monitoring; Antidepressants; Psychotropic Medications/Drugs; Lab-Clinic Collaboration.
<p>Background and Aim: Drug-induced thrombocytopenia (DIT) is a rare but potentially life-threatening condition triggered by certain medications. This report aims to emphasize the importance of early diagnosis and appropriate management of DIT in patients with Major Depressive Disorder (MDD) treated with a polypharmacy regimen. <br>Case Presentation: A case study of a 39-year-old woman with MDD who developed bleeding following treatment with “aripiprazole”, “olanzapine”, “lorazepam”, and “sodium valproate” is presented.  <br>Conclusion: The patient’s condition improved significantly after medication changes and close collaboration between psychiatrists and hematologists. This highlights the need for proper care and correct prescription of medicines for patients with MDD. <br>Laboratory Highlights & Technical Implications: This case report demonstrates the need for: <br>•    Enhanced CBC review protocols for patients receiving psychiatric care/treatment who are on polypharmacy; •     Reflex testing algorithms for thrombocytopenia (low platelet count) workups; <br>•    Standardized communication channels between lab and mental health teams. </p>
title DRUG-INDUCED THROMBOCYTOPENIA IN PSYCHIATRIC PATIENTS: EARLY RECOGNITION AND CASE-BASED MULTIDISCIPLINARY MANAGEMENT
topic Drug-Induced Thrombocytopenia; Platelet; Major Depressive Disorder (MDD); CBC Monitoring; Antidepressants; Psychotropic Medications/Drugs; Lab-Clinic Collaboration.
url https://doi.org/10.5281/zenodo.18936145