Gut Microbiota Mediates Local Kynurenine Pathway Activity Independently of Inflammation Through Host Micronutrient Absorption

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Auteurs principaux: Djukovic, Ana, Liao, Chen, Bimbo Szuhai, Andras, Lindberg, Chloe, Xavier, Joao
Format: Recurso digital
Publié: Zenodo 2026
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author Djukovic, Ana
Liao, Chen
Bimbo Szuhai, Andras
Lindberg, Chloe
Xavier, Joao
author_facet Djukovic, Ana
Liao, Chen
Bimbo Szuhai, Andras
Lindberg, Chloe
Xavier, Joao
contents <p>This repository contains the data and associated materials from the study <strong>Gut Microbiota Mediates Local Kynurenine Pathway Activity Independently of Inflammation Through Host Micronutrient Absorption</strong>. The dataset was generated to investigate the role of the gut microbiota in host tryptophan metabolism and its implications for immunity.</p> <p>The repository includes 16S rDNA microbiome sequencing data, small intestine RNA sequencing data, colonic IDO1 expression levels, colon cross-section histology slides and cell quantification, metabolic profiling from different sample types (mouse feces, cecal content & tissue, plasma, allo-HCT patients feces & plasma), and metadata describing the experimental samples.</p> <p>Detailed methodological descriptions are provided in the associated manuscript.</p> <h3>Data Usage</h3> <p>The dataset is released for academic and research purposes. Users are encouraged to cite both this Zenodo record and the associated publication when using these data.</p> <h3>Contact</h3> <p>For questions regarding the dataset, please contact:<br>Ana Djukovic - Centro de Investigación Príncipe Felipe - adjukovic@cipf.es</p>
format Recurso digital
id zenodo_https___doi_org_10_5281_zenodo_18937393
institution Zenodo
language
publishDate 2026
publisher Zenodo
record_format zenodo
spellingShingle Gut Microbiota Mediates Local Kynurenine Pathway Activity Independently of Inflammation Through Host Micronutrient Absorption
Djukovic, Ana
Liao, Chen
Bimbo Szuhai, Andras
Lindberg, Chloe
Xavier, Joao
Gastrointestinal Microbiome
gamma-tocotrienol
kynurenine pathway
Lachnospiraceae
Oscillospiraceae
Immunity/immunology
IBD
<p>This repository contains the data and associated materials from the study <strong>Gut Microbiota Mediates Local Kynurenine Pathway Activity Independently of Inflammation Through Host Micronutrient Absorption</strong>. The dataset was generated to investigate the role of the gut microbiota in host tryptophan metabolism and its implications for immunity.</p> <p>The repository includes 16S rDNA microbiome sequencing data, small intestine RNA sequencing data, colonic IDO1 expression levels, colon cross-section histology slides and cell quantification, metabolic profiling from different sample types (mouse feces, cecal content & tissue, plasma, allo-HCT patients feces & plasma), and metadata describing the experimental samples.</p> <p>Detailed methodological descriptions are provided in the associated manuscript.</p> <h3>Data Usage</h3> <p>The dataset is released for academic and research purposes. Users are encouraged to cite both this Zenodo record and the associated publication when using these data.</p> <h3>Contact</h3> <p>For questions regarding the dataset, please contact:<br>Ana Djukovic - Centro de Investigación Príncipe Felipe - adjukovic@cipf.es</p>
title Gut Microbiota Mediates Local Kynurenine Pathway Activity Independently of Inflammation Through Host Micronutrient Absorption
topic Gastrointestinal Microbiome
gamma-tocotrienol
kynurenine pathway
Lachnospiraceae
Oscillospiraceae
Immunity/immunology
IBD
url https://doi.org/10.5281/zenodo.18937393