SOVEREIGN VEGAN ORGANIC PHYTO- MODULATION OF BRAIN CANCER: A GOOGLE PILLS PHYTOINTELLIGENCE 3.1 PROPOSED PROTOCOL
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| Natura: | Recurso digital |
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Zenodo
2026
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| _version_ | 1866901687251238912 |
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| author | Landry, Marie Seshat |
| author_facet | Landry, Marie Seshat |
| contents | <p>Glioblastoma multiforme (GBM) and other high-grade gliomas represent a therapeutic challenge due to the blood-brain barrier (BBB) and a highly immunosuppressive tumor microenvironment (TME). This study explores a multi-targeted phytochemical protocol designed to modulate the inflammatory cascade driving tumorigenesis. Specifically, we investigate the suppression of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway and the subsequent downregulation of pro-inflammatory cytokines, specifically Interleukin-1 beta (IL-1β) and Tumor Necrosis Factor-alpha (TNF-α). By concurrently activating the NRF2 antioxidant pathway, this protocol aims to induce oxidative stress specifically within tumor cells whileprotecting healthy neuronal tissue, offering a novel metabolic deconvolution of brain cancer progression.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19016031 |
| institution | Zenodo |
| language | |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | SOVEREIGN VEGAN ORGANIC PHYTO- MODULATION OF BRAIN CANCER: A GOOGLE PILLS PHYTOINTELLIGENCE 3.1 PROPOSED PROTOCOL Landry, Marie Seshat <p>Glioblastoma multiforme (GBM) and other high-grade gliomas represent a therapeutic challenge due to the blood-brain barrier (BBB) and a highly immunosuppressive tumor microenvironment (TME). This study explores a multi-targeted phytochemical protocol designed to modulate the inflammatory cascade driving tumorigenesis. Specifically, we investigate the suppression of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway and the subsequent downregulation of pro-inflammatory cytokines, specifically Interleukin-1 beta (IL-1β) and Tumor Necrosis Factor-alpha (TNF-α). By concurrently activating the NRF2 antioxidant pathway, this protocol aims to induce oxidative stress specifically within tumor cells whileprotecting healthy neuronal tissue, offering a novel metabolic deconvolution of brain cancer progression.</p> |
| title | SOVEREIGN VEGAN ORGANIC PHYTO- MODULATION OF BRAIN CANCER: A GOOGLE PILLS PHYTOINTELLIGENCE 3.1 PROPOSED PROTOCOL |
| url | https://doi.org/10.5281/zenodo.19016031 |