Usefulness of nutritional screening for correlation with morbidity and mortality in septic and non-septic patients in the Intensive Care Unit
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| author | Manzo, Palacios Ervin García, Miranda GM De la Cruz, López José Quevedo, Samaniego Edgar Alejandro Rojas, Rojas Alejandro |
| author_facet | Manzo, Palacios Ervin García, Miranda GM De la Cruz, López José Quevedo, Samaniego Edgar Alejandro Rojas, Rojas Alejandro |
| contents | <p><span lang="EN-US">ABSTRACT</span></p> <p><span lang="EN-US"> </span></p> <p><span lang="ES-MX">BACKGROUND</span></p> <p><span><span lang="EN">Advances in basic and clinical research have allowed physicians to understand the metabolic response to trauma in postoperative and/or infected patients, which results in exaggerated catabolism due to their underlying pathology, prolonged fasting, and inability to adapt. <sup>1</sup> </span></span></p> <p><span><span lang="EN">Nutritional support is a routine part of ICU therapy. Treating and preventing malnutrition and nutrient deficiencies is recommended and generally benefits patient outcomes, although adverse effects and complications can occur.</span></span></p> <p><span lang="EN-US">METHODS</span></p> <p><span><span lang="EN">A prospective, longitudinal, observational, comparative study was conducted in the Intensive Care Unit of The Hospital Angeles Metropolitano.</span></span></p> <p><span><span lang="EN">Patients were selected from a cohort admitted to the Intensive Care Unit and who met the inclusion criteria.</span></span></p> <p><span><span lang="EN">Inclusion criteria: Patients admitted to the Intensive Care Unit with various diagnoses for management were calculated as percentage of ideal body weight; percentage of usual body weight, percentage of weight change; Arm circumference, triceps skinfold, arm muscle circumference, creatinine-height ratio, albumin and total lymphocyte count, Karnofsky, indexed body mass index (BMIi), Body Mass Index. A nutritional clinical history was taken with the main focus on changes in body weight, changes in diet in relation to normal, gastrointestinal symptoms (persistent greater than 2 weeks), functional capacity, disease and its relationship with nutritional requirements. Physical examination: loss of skin fat, muscle atrophy, edema</span></span></p> <p><span lang="EN-US"> </span></p> <p><span lang="EN-US">RESULTS</span></p> <p><span lang="EN-US">We incluyed Fourty<span> </span>patients, 19 female (47.5%) and 21 male (52.5%) and divided in two groups.</span></p> <p><span lang="EN-US"><span> </span><span> </span>Septic group (9 patients)<span> </span><span> </span>Group Non Septic(31 patients)<span> </span></span></p> <p><span lang="EN-US">Age:<span> </span><span> </span>56 </span><span lang="EN-US">±</span><span lang="EN-US">14.72 years old<span> </span><span> </span>61.75 </span><span lang="EN-US">±</span><span lang="EN-US">15.61 years old<span> </span></span></p> <p><span lang="EN-US">Sex: Male<span> </span><span> </span><span> </span>55.55%<span> </span><span> </span>51.61%<span> </span><span> </span></span></p> <p><span lang="EN-US"><span> </span>Female <span> </span>44.44%<span> </span><span> </span>48.38%<span> </span></span></p> <pre><span><span lang="EN">The associated pathologies that led to admission to the Intensive Care Unit were the following: Acute Ischemic Heart Disease: (13</span></span><span lang="EN"> </span><span lang="EN-US">patients</span><span><span lang="EN">) 32.5%, Diabetes mellitus and complications ( 6</span></span><span lang="EN"> </span><span lang="EN-US">patients</span><span><span lang="EN"> ) 15%; abdominal sepsis ( 4 </span></span><span lang="EN-US">patients</span><span><span lang="EN">) 10%, Neurological Vascular Disease: ( 3 </span></span><span lang="EN-US">patients</span><span><span lang="EN">) 7.5%; Acute Respiratory Tract Infection ( 2 </span></span><span lang="EN-US">patients</span><span><span lang="EN">) 5%, Acute Pancreatitis ( 2</span></span><span lang="EN"> </span><span lang="EN-US">patients</span><span><span lang="EN"> ) 5%, hypovolemic shock (2</span></span><span lang="EN"> </span><span lang="EN-US">patients</span><span><span lang="EN">) 5%, Hypertensive Emergency (1 </span></span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%, Chronic Obstructive Pulmonary Disease (1</span></span><span lang="EN"> </span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%; Venous Congestive Heart Failure (1</span></span><span lang="EN"> </span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%; Status Epilepticus (1</span></span><span lang="EN"> </span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%; perirenal abscess (1</span></span><span lang="EN"> </span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%.</span></span></pre> <pre><span><strong><span lang="EN">Main Measurements and Results:</span></strong></span></pre> <pre><span><span lang="EN">Albumin: 2.59 ± 0.84 g/dL; Total lymphocyte count: 1,500.84 ± 1,530.08; Arm circumference: 28.92 ± 2.97 cm; PCT: 19.57 ± 7.74 cm; % PCI: 117.48 ± 19.62 cm; % PCU: 98.62 ± 4.33; % Weight change: 1.31 ± 4.17%; CMB: 29.28 ± 6.68; IC/T: 170.89 ± 405.75; IMCi: 55.35 ± 7.35; BMI: 27.68 ± 4.54; Costs/Day: $85,843.75 ± $76,973.49; Karnofsky Score: 93.5 ± 13.50; Age: 75.4 ± 22.04 years. Subjective Global Assessment: Well-nourished: 72.50%; Moderately malnourished or at risk of malnutrition: 22.50%; Severely malnourished: 5%.</span></span></pre> <pre><span><span lang="EN">Regarding the correlation of the different variables, it was as follows: days of stay – Serum albumin level: r = -0.330 < 0.05;</span></span><span><span lang="EN"> </span></span><span><span lang="EN">days of stay – Karnofsky Score: r = -0.504 < 0.01; Albumin – days of stay</span></span></pre> <pre><span><span lang="EN">: r = -0.330 < 0.05.;</span></span><span><span lang="EN"> </span></span><span><span lang="EN">Arm circumference – PCT: r = 0.655 - 0.01; Arm circumference - % PCI: r = 0.658 < 0.01; PCT - % PCI: r = 0.447 - 0.01; PCT - Moderately malnourished or at risk of malnutrition: r = 0.865 - 0.01; %PCI - % Weight change: r = -0.997 - 0.01; Karnofsky score- days of stay: r = -0.504 - 0.01; Severely malnourished - days of stay: r = 1.000 - 0.01; Severely malnourished - albumin: </span></span></pre> <pre><span><span lang="EN">r = 1.000 - 0.01; Severely malnourished - Total lymphocyte count: r = -1.000 - 0.01; Severely malnourished – arm circumference: r= -1.000 - 0.01; Severely malnourished- PCT: r= -1.000 - 0.01; Severely malnourished- %PCI: r= -1.000 - 0.01; Severely malnourished-%PCU: r= 1.000 - 0.01; Severely malnourished-% Weight change: r= -1.000 - 0.01; Severely malnourished- Karnofsky score: r= -1.000 - 0.01;</span></span><span><span lang="EN"> </span></span><span><span lang="EN">Severely malnourished - Age: r = -1.000 - 0.01; CMB - arm circumference: r = 0.422 - 0.01; CMB - % PCI: r = 0.353 - 0.05; IC/T - Well-nourished: r = 0.882<span> </span>- 0.01; Improvement - PCT: r = 0.416 < 0.05; Improvement - Well-nourished: r = 0.986 - 0.01;Improvement - Moderately malnourished or at risk of malnutrition: r = 0.993 - 0.01; BMI - Well-nourished: r = 0.461 < 0.05; BMI - <span> </span>Arm circumference: r = 0.645 - 0.01; BMI – PCT: r= .434 - 0.01; BMI - % PCI: r= .938 -0.01; Costs – days of stay: r= 1.000 - 0.01; Costs – albumin: r= -.330 -0.05; Costs – Karnofsky score: r= -.504 p< 0.01</span></span></pre> <pre><span><span lang="EN">Regarding the septic and non-septic groups: The variables that had statistical significance were the following: % change in weight 1.914 </span></span><span lang="EN">r = </span><span><span lang="EN">0.025 p< 0.05; BMIi 2.579 <span> </span>r= 0.01 p-0.05; Costs/day 3.184 r = 0.01 p < 0.05, Days of stay: 3.184</span></span><span lang="EN-US">±</span><span><span lang="EN"> 0.025 r=-0.01 p < 0.05<span> </span>p value < 0.05.</span></span></pre> <p><span lang="EN-US"> </span></p> <p><span lang="EN-US">Conclusions</span></p> <p><span lang="EN-US">The data of more correlation in the evaluation are: the levels of serum albumin, It counts total of lymphocyte , stay days-costs and mortality.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19177602 |
| institution | Zenodo |
| language | eng |
| publishDate | 2026 |
| publisher | Zenodo |
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| spellingShingle | Usefulness of nutritional screening for correlation with morbidity and mortality in septic and non-septic patients in the Intensive Care Unit Manzo, Palacios Ervin García, Miranda GM De la Cruz, López José Quevedo, Samaniego Edgar Alejandro Rojas, Rojas Alejandro Nutritional screening, correlation with morbidity and mortality in septic and non-septic, Intensive Care Unit <p><span lang="EN-US">ABSTRACT</span></p> <p><span lang="EN-US"> </span></p> <p><span lang="ES-MX">BACKGROUND</span></p> <p><span><span lang="EN">Advances in basic and clinical research have allowed physicians to understand the metabolic response to trauma in postoperative and/or infected patients, which results in exaggerated catabolism due to their underlying pathology, prolonged fasting, and inability to adapt. <sup>1</sup> </span></span></p> <p><span><span lang="EN">Nutritional support is a routine part of ICU therapy. Treating and preventing malnutrition and nutrient deficiencies is recommended and generally benefits patient outcomes, although adverse effects and complications can occur.</span></span></p> <p><span lang="EN-US">METHODS</span></p> <p><span><span lang="EN">A prospective, longitudinal, observational, comparative study was conducted in the Intensive Care Unit of The Hospital Angeles Metropolitano.</span></span></p> <p><span><span lang="EN">Patients were selected from a cohort admitted to the Intensive Care Unit and who met the inclusion criteria.</span></span></p> <p><span><span lang="EN">Inclusion criteria: Patients admitted to the Intensive Care Unit with various diagnoses for management were calculated as percentage of ideal body weight; percentage of usual body weight, percentage of weight change; Arm circumference, triceps skinfold, arm muscle circumference, creatinine-height ratio, albumin and total lymphocyte count, Karnofsky, indexed body mass index (BMIi), Body Mass Index. A nutritional clinical history was taken with the main focus on changes in body weight, changes in diet in relation to normal, gastrointestinal symptoms (persistent greater than 2 weeks), functional capacity, disease and its relationship with nutritional requirements. Physical examination: loss of skin fat, muscle atrophy, edema</span></span></p> <p><span lang="EN-US"> </span></p> <p><span lang="EN-US">RESULTS</span></p> <p><span lang="EN-US">We incluyed Fourty<span> </span>patients, 19 female (47.5%) and 21 male (52.5%) and divided in two groups.</span></p> <p><span lang="EN-US"><span> </span><span> </span>Septic group (9 patients)<span> </span><span> </span>Group Non Septic(31 patients)<span> </span></span></p> <p><span lang="EN-US">Age:<span> </span><span> </span>56 </span><span lang="EN-US">±</span><span lang="EN-US">14.72 years old<span> </span><span> </span>61.75 </span><span lang="EN-US">±</span><span lang="EN-US">15.61 years old<span> </span></span></p> <p><span lang="EN-US">Sex: Male<span> </span><span> </span><span> </span>55.55%<span> </span><span> </span>51.61%<span> </span><span> </span></span></p> <p><span lang="EN-US"><span> </span>Female <span> </span>44.44%<span> </span><span> </span>48.38%<span> </span></span></p> <pre><span><span lang="EN">The associated pathologies that led to admission to the Intensive Care Unit were the following: Acute Ischemic Heart Disease: (13</span></span><span lang="EN"> </span><span lang="EN-US">patients</span><span><span lang="EN">) 32.5%, Diabetes mellitus and complications ( 6</span></span><span lang="EN"> </span><span lang="EN-US">patients</span><span><span lang="EN"> ) 15%; abdominal sepsis ( 4 </span></span><span lang="EN-US">patients</span><span><span lang="EN">) 10%, Neurological Vascular Disease: ( 3 </span></span><span lang="EN-US">patients</span><span><span lang="EN">) 7.5%; Acute Respiratory Tract Infection ( 2 </span></span><span lang="EN-US">patients</span><span><span lang="EN">) 5%, Acute Pancreatitis ( 2</span></span><span lang="EN"> </span><span lang="EN-US">patients</span><span><span lang="EN"> ) 5%, hypovolemic shock (2</span></span><span lang="EN"> </span><span lang="EN-US">patients</span><span><span lang="EN">) 5%, Hypertensive Emergency (1 </span></span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%, Chronic Obstructive Pulmonary Disease (1</span></span><span lang="EN"> </span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%; Venous Congestive Heart Failure (1</span></span><span lang="EN"> </span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%; Status Epilepticus (1</span></span><span lang="EN"> </span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%; perirenal abscess (1</span></span><span lang="EN"> </span><span lang="EN-US">patient</span><span><span lang="EN">) 2.5%.</span></span></pre> <pre><span><strong><span lang="EN">Main Measurements and Results:</span></strong></span></pre> <pre><span><span lang="EN">Albumin: 2.59 ± 0.84 g/dL; Total lymphocyte count: 1,500.84 ± 1,530.08; Arm circumference: 28.92 ± 2.97 cm; PCT: 19.57 ± 7.74 cm; % PCI: 117.48 ± 19.62 cm; % PCU: 98.62 ± 4.33; % Weight change: 1.31 ± 4.17%; CMB: 29.28 ± 6.68; IC/T: 170.89 ± 405.75; IMCi: 55.35 ± 7.35; BMI: 27.68 ± 4.54; Costs/Day: $85,843.75 ± $76,973.49; Karnofsky Score: 93.5 ± 13.50; Age: 75.4 ± 22.04 years. Subjective Global Assessment: Well-nourished: 72.50%; Moderately malnourished or at risk of malnutrition: 22.50%; Severely malnourished: 5%.</span></span></pre> <pre><span><span lang="EN">Regarding the correlation of the different variables, it was as follows: days of stay – Serum albumin level: r = -0.330 < 0.05;</span></span><span><span lang="EN"> </span></span><span><span lang="EN">days of stay – Karnofsky Score: r = -0.504 < 0.01; Albumin – days of stay</span></span></pre> <pre><span><span lang="EN">: r = -0.330 < 0.05.;</span></span><span><span lang="EN"> </span></span><span><span lang="EN">Arm circumference – PCT: r = 0.655 - 0.01; Arm circumference - % PCI: r = 0.658 < 0.01; PCT - % PCI: r = 0.447 - 0.01; PCT - Moderately malnourished or at risk of malnutrition: r = 0.865 - 0.01; %PCI - % Weight change: r = -0.997 - 0.01; Karnofsky score- days of stay: r = -0.504 - 0.01; Severely malnourished - days of stay: r = 1.000 - 0.01; Severely malnourished - albumin: </span></span></pre> <pre><span><span lang="EN">r = 1.000 - 0.01; Severely malnourished - Total lymphocyte count: r = -1.000 - 0.01; Severely malnourished – arm circumference: r= -1.000 - 0.01; Severely malnourished- PCT: r= -1.000 - 0.01; Severely malnourished- %PCI: r= -1.000 - 0.01; Severely malnourished-%PCU: r= 1.000 - 0.01; Severely malnourished-% Weight change: r= -1.000 - 0.01; Severely malnourished- Karnofsky score: r= -1.000 - 0.01;</span></span><span><span lang="EN"> </span></span><span><span lang="EN">Severely malnourished - Age: r = -1.000 - 0.01; CMB - arm circumference: r = 0.422 - 0.01; CMB - % PCI: r = 0.353 - 0.05; IC/T - Well-nourished: r = 0.882<span> </span>- 0.01; Improvement - PCT: r = 0.416 < 0.05; Improvement - Well-nourished: r = 0.986 - 0.01;Improvement - Moderately malnourished or at risk of malnutrition: r = 0.993 - 0.01; BMI - Well-nourished: r = 0.461 < 0.05; BMI - <span> </span>Arm circumference: r = 0.645 - 0.01; BMI – PCT: r= .434 - 0.01; BMI - % PCI: r= .938 -0.01; Costs – days of stay: r= 1.000 - 0.01; Costs – albumin: r= -.330 -0.05; Costs – Karnofsky score: r= -.504 p< 0.01</span></span></pre> <pre><span><span lang="EN">Regarding the septic and non-septic groups: The variables that had statistical significance were the following: % change in weight 1.914 </span></span><span lang="EN">r = </span><span><span lang="EN">0.025 p< 0.05; BMIi 2.579 <span> </span>r= 0.01 p-0.05; Costs/day 3.184 r = 0.01 p < 0.05, Days of stay: 3.184</span></span><span lang="EN-US">±</span><span><span lang="EN"> 0.025 r=-0.01 p < 0.05<span> </span>p value < 0.05.</span></span></pre> <p><span lang="EN-US"> </span></p> <p><span lang="EN-US">Conclusions</span></p> <p><span lang="EN-US">The data of more correlation in the evaluation are: the levels of serum albumin, It counts total of lymphocyte , stay days-costs and mortality.</span></p> |
| title | Usefulness of nutritional screening for correlation with morbidity and mortality in septic and non-septic patients in the Intensive Care Unit |
| topic | Nutritional screening, correlation with morbidity and mortality in septic and non-septic, Intensive Care Unit |
| url | https://doi.org/10.5281/zenodo.19177602 |