Statistical analysis plan v. 1.2: Classroom air purifiers for reducing school absence: protocol for a pragmatic cluster-randomized, parallel, two-arm, group sequential superiority trial
Fuente:
Zenodo
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Recurso digital |
| Published: |
Zenodo
2026
|
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1866901710500265984 |
|---|---|
| author | Rose, Christopher James Solberg, Runar |
| author_facet | Rose, Christopher James Solberg, Runar |
| contents | <p><span lang="EN-US">Respiratory infections like influenza and SARS-CoV-2 pose significant global health risks due to their potential high transmissibility and severity. SARS-CoV-2 has caused over 7 million deaths worldwide, and the Lancet Commission estimates a >20% chance of another respiratory virus pandemic within a decade. Schools are high-risk settings for transmission, with outbreaks causing substantial disruptions for teachers, students, and parents. While school closures reduce transmission, they can also lead to learning loss and societal burdens. Air purifiers with HEPA filters may offer a non-disruptive mitigation strategy, but at the time of writing only one randomized trial has been conducted, with unpublished results, highlighting the need for further research.</span></p> <p><span lang="EN-US">This statistical analysis plan describes the analysis for a cluster-randomized, parallel, two-arm, group sequential superiority trial that aims to estimate the effect of air purifiers compared to sham air purifiers on absenteeism among primary school children in Norway (primary research question); secondary research questions are listed below.</span></p> <p><span lang="EN-US">The trial protocol is available here: https://bmjopen.bmj.com/content/15/12/e109659#DC3</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19237517 |
| institution | Zenodo |
| language | |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Statistical analysis plan v. 1.2: Classroom air purifiers for reducing school absence: protocol for a pragmatic cluster-randomized, parallel, two-arm, group sequential superiority trial Rose, Christopher James Solberg, Runar <p><span lang="EN-US">Respiratory infections like influenza and SARS-CoV-2 pose significant global health risks due to their potential high transmissibility and severity. SARS-CoV-2 has caused over 7 million deaths worldwide, and the Lancet Commission estimates a >20% chance of another respiratory virus pandemic within a decade. Schools are high-risk settings for transmission, with outbreaks causing substantial disruptions for teachers, students, and parents. While school closures reduce transmission, they can also lead to learning loss and societal burdens. Air purifiers with HEPA filters may offer a non-disruptive mitigation strategy, but at the time of writing only one randomized trial has been conducted, with unpublished results, highlighting the need for further research.</span></p> <p><span lang="EN-US">This statistical analysis plan describes the analysis for a cluster-randomized, parallel, two-arm, group sequential superiority trial that aims to estimate the effect of air purifiers compared to sham air purifiers on absenteeism among primary school children in Norway (primary research question); secondary research questions are listed below.</span></p> <p><span lang="EN-US">The trial protocol is available here: https://bmjopen.bmj.com/content/15/12/e109659#DC3</span></p> |
| title | Statistical analysis plan v. 1.2: Classroom air purifiers for reducing school absence: protocol for a pragmatic cluster-randomized, parallel, two-arm, group sequential superiority trial |
| url | https://doi.org/10.5281/zenodo.19237517 |