V120:Bio-SYNC Protocol — Testing Life as a Long-Wavelength Synchronization Receiver: A Safe-Escalation Framework from Gravimetric Lock-In to Microgravity Hysteresis
Fuente:
Zenodo
Salvato in:
| Autori principali: | , , , |
|---|---|
| Natura: | Recurso digital |
| Pubblicazione: |
Zenodo
2026
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1866901141185363968 |
|---|---|
| author | Yoshida, Satoshi ChatGPT, A. Gemini, G. Claude, C. |
| author_facet | Yoshida, Satoshi ChatGPT, A. Gemini, G. Claude, C. |
| contents | <p>Standard biology already recognizes gravity sensing in multiple forms: vertebrate vestibular systems detect gravito-inertial input through otolith organs, plants respond through statolith-based gravitropism, and many cell types exhibit gravity-sensitive mechanotransduction via Piezo1, YAP/TAZ, and the actin cytoskeleton. Therefore, the decisive question is no longer whether life senses gravity at all, but whether there exists a residual ultra-low-frequency synchronization response that remains after known mechanosensory pathways are accounted for.</p> <p>We propose the Bio-SYNC Protocol, a falsifiable, protocol-first framework designed to test this possibility. The core question is: Does phase-locked biological synchrony remain as a residual after subtraction, suppression, or regression of known mechanotransduction pathways?</p> <p>Within the YAGC framework — motivated by the synchronization-mesh concept (V113) and the distance-dependent synchronization relaxation time τ_c ∝ √R (V114) — we hypothesize that extremely long-wavelength synchronization fluctuations may couple to spatially distributed biological networks as weak coherent phase modulation. This leads to three quantitative expectations: (1) lock-in sensitivity scales with system size as S ∝ L^α with prior range 0 < α ≤ 1; (2) a connectivity threshold p_c exists below which synchrony collapses; (3) microgravity-induced memory effects obey a hysteresis timescale τ_hyst ∝ L^β (β > 0), interpreted through the No-Disposal Principle.<br><br></p> <p>The protocol is implemented in a safe-escalation design: Phase 0 (natural gravimetric lock-in), Phase 1 (artificial modulation with sham control, mechanosensor suppression, scaling, and stochastic-resonance testing), and Phase 2 (microgravity hysteresis). A Bio-SYNC-positive result requires simultaneous fulfillment of four conditions: phase-locking at preregistered frequencies, disappearance under sham, persistence after environmental covariate regression, and residual synchrony after suppression of known mechanosensors.</p> <p>Appendix D provides a literature map reclassifying existing studies across chronobiology, gravisensing, mechanobiology, vestibular science, and microgravity physiology into historical precursors, candidate systems, near-precedents, and null controls — showing where V120 attaches to existing work and where the real untested gaps remain.</p> <p>V120 is submitted not as evidence of a discovered biological gravity receiver, but as a falsifiable protocol that defines how such a claim must fail or survive.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19342801 |
| institution | Zenodo |
| language | |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | V120:Bio-SYNC Protocol — Testing Life as a Long-Wavelength Synchronization Receiver: A Safe-Escalation Framework from Gravimetric Lock-In to Microgravity Hysteresis Yoshida, Satoshi ChatGPT, A. Gemini, G. Claude, C. synchronization gravimetric tide mechanotransduction phase locking lock-in detection microgravity hysteresis stochastic resonance Bio-SYNC YAGC residual analysis circatidal rhythm phased array percolation threshold No-Disposal Principle biological gravity sensing protocol paper <p>Standard biology already recognizes gravity sensing in multiple forms: vertebrate vestibular systems detect gravito-inertial input through otolith organs, plants respond through statolith-based gravitropism, and many cell types exhibit gravity-sensitive mechanotransduction via Piezo1, YAP/TAZ, and the actin cytoskeleton. Therefore, the decisive question is no longer whether life senses gravity at all, but whether there exists a residual ultra-low-frequency synchronization response that remains after known mechanosensory pathways are accounted for.</p> <p>We propose the Bio-SYNC Protocol, a falsifiable, protocol-first framework designed to test this possibility. The core question is: Does phase-locked biological synchrony remain as a residual after subtraction, suppression, or regression of known mechanotransduction pathways?</p> <p>Within the YAGC framework — motivated by the synchronization-mesh concept (V113) and the distance-dependent synchronization relaxation time τ_c ∝ √R (V114) — we hypothesize that extremely long-wavelength synchronization fluctuations may couple to spatially distributed biological networks as weak coherent phase modulation. This leads to three quantitative expectations: (1) lock-in sensitivity scales with system size as S ∝ L^α with prior range 0 < α ≤ 1; (2) a connectivity threshold p_c exists below which synchrony collapses; (3) microgravity-induced memory effects obey a hysteresis timescale τ_hyst ∝ L^β (β > 0), interpreted through the No-Disposal Principle.<br><br></p> <p>The protocol is implemented in a safe-escalation design: Phase 0 (natural gravimetric lock-in), Phase 1 (artificial modulation with sham control, mechanosensor suppression, scaling, and stochastic-resonance testing), and Phase 2 (microgravity hysteresis). A Bio-SYNC-positive result requires simultaneous fulfillment of four conditions: phase-locking at preregistered frequencies, disappearance under sham, persistence after environmental covariate regression, and residual synchrony after suppression of known mechanosensors.</p> <p>Appendix D provides a literature map reclassifying existing studies across chronobiology, gravisensing, mechanobiology, vestibular science, and microgravity physiology into historical precursors, candidate systems, near-precedents, and null controls — showing where V120 attaches to existing work and where the real untested gaps remain.</p> <p>V120 is submitted not as evidence of a discovered biological gravity receiver, but as a falsifiable protocol that defines how such a claim must fail or survive.</p> |
| title | V120:Bio-SYNC Protocol — Testing Life as a Long-Wavelength Synchronization Receiver: A Safe-Escalation Framework from Gravimetric Lock-In to Microgravity Hysteresis |
| topic | synchronization gravimetric tide mechanotransduction phase locking lock-in detection microgravity hysteresis stochastic resonance Bio-SYNC YAGC residual analysis circatidal rhythm phased array percolation threshold No-Disposal Principle biological gravity sensing protocol paper |
| url | https://doi.org/10.5281/zenodo.19342801 |