A Review on Solid Lipid Nano Particles: Design, Characterization & Therapeutic Applications
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2026
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| _version_ | 1866901221490556928 |
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| author | Gurajala Tejesh*, Dr M. Sunitha Reddy, Dr K. Anie Vijetha |
| author_facet | Gurajala Tejesh*, Dr M. Sunitha Reddy, Dr K. Anie Vijetha |
| contents | <p><span>Solid lipid nanoparticles have become a promising nano-carrier system for improving drug delivery and therapeutic efficacy. These SLNPs systems provide the advantages of both lipid formulations and polymeric nanoparticles by enhancing biocompatibility, controll drug release with an increase in stability. SLNPs are widely used for both hydrophilic and lipophilic drugs through different routes of administration. The preparation methods of solid lipid nanoparticles are high-pressure homogenisation, solvent evaporation, solvent injection method, double emulsion, etc. Characterisation parameters are zeta potential, SEM, TEM, FTIR, and entrapment efficiency, which plays an important role in determining their performance. This review article mainly focuses on SLNPs' structure, types of material used, method of preparation, advantages, disadvantages, characterisation, and applications of SLNPS.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19414431 |
| institution | Zenodo |
| language | |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | A Review on Solid Lipid Nano Particles: Design, Characterization & Therapeutic Applications Gurajala Tejesh*, Dr M. Sunitha Reddy, Dr K. Anie Vijetha solid lipid nanoparticles, High-pressure homogenisation, entrapment efficiency, drug delivery <p><span>Solid lipid nanoparticles have become a promising nano-carrier system for improving drug delivery and therapeutic efficacy. These SLNPs systems provide the advantages of both lipid formulations and polymeric nanoparticles by enhancing biocompatibility, controll drug release with an increase in stability. SLNPs are widely used for both hydrophilic and lipophilic drugs through different routes of administration. The preparation methods of solid lipid nanoparticles are high-pressure homogenisation, solvent evaporation, solvent injection method, double emulsion, etc. Characterisation parameters are zeta potential, SEM, TEM, FTIR, and entrapment efficiency, which plays an important role in determining their performance. This review article mainly focuses on SLNPs' structure, types of material used, method of preparation, advantages, disadvantages, characterisation, and applications of SLNPS.</span></p> |
| title | A Review on Solid Lipid Nano Particles: Design, Characterization & Therapeutic Applications |
| topic | solid lipid nanoparticles, High-pressure homogenisation, entrapment efficiency, drug delivery |
| url | https://doi.org/10.5281/zenodo.19414431 |