The Continuous Fragility Quotient as a Model-Free Assessment for Continuous Outcomes
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| Format: | Recurso digital |
| Sprache: | Englisch |
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Zenodo
2026
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| _version_ | 1866901679961538560 |
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| author | Heston, Thomas F |
| author_facet | Heston, Thomas F |
| contents | <p>The continuous fragility quotient (CFQ) is a model-free fragility metric for continuous outcomes that derives entirely from the Welch t-statistic geometry, requiring only published summary statistics. Unlike the continuous fragility index (CFI), which reconstructs pseudo-observations under distributional assumptions, CFQ produces a unique, analyst-independent value normalized to [0,1] for cross-study comparison. CFQ pairs with the Meaningful Change Index (MeCI) to complete the p–fr–nb triplet for continuous outcome trials.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19445025 |
| institution | Zenodo |
| language | eng |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | The Continuous Fragility Quotient as a Model-Free Assessment for Continuous Outcomes Heston, Thomas F continuous fragility quotient CFQ statistical fragility model-free statistics continuous outcomes Welch t-test fragility index global fragility index evidence quality p-value limitations neutrality boundary framework <p>The continuous fragility quotient (CFQ) is a model-free fragility metric for continuous outcomes that derives entirely from the Welch t-statistic geometry, requiring only published summary statistics. Unlike the continuous fragility index (CFI), which reconstructs pseudo-observations under distributional assumptions, CFQ produces a unique, analyst-independent value normalized to [0,1] for cross-study comparison. CFQ pairs with the Meaningful Change Index (MeCI) to complete the p–fr–nb triplet for continuous outcome trials.</p> |
| title | The Continuous Fragility Quotient as a Model-Free Assessment for Continuous Outcomes |
| topic | continuous fragility quotient CFQ statistical fragility model-free statistics continuous outcomes Welch t-test fragility index global fragility index evidence quality p-value limitations neutrality boundary framework |
| url | https://doi.org/10.5281/zenodo.19445025 |