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| Format: | Recurso digital |
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Zenodo
2026
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| Online Access: | https://doi.org/10.5281/zenodo.19592538 |
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Table of Contents:
- <p class="MsoNormal"><em><span>Entamoeba moshkovskii</span></em><span>, a morphological twin of <em>Entamoeba histolytica</em>–the human pathogen, exhibits extraordinary environmental resilience, thriving in hyper-eutrophic niches that are lethal to its parasitic relatives. In this study, we employed a multi-level “stability-based proteomic sieve” to elucidate the molecular drivers of this persistence using bioinformatic analysis. By comparing the top stable proteins across inter-genus (<em>Acanthamoeba </em>vs. <em>Entamoeba</em>) and intra-genus (<em>E. moshkovskii</em> vs. <em>E. histolytica/E. dispar</em> vs. <em>E. marina</em>) lineages, we identified a “<strong>Resilient 18</strong>” toolkit–a specialized set of proteins with extreme structural stability (Instability Index as low as 20).</span></p>