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| Format: | Recurso digital |
| Language: | English |
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2026
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| Online Access: | https://doi.org/10.5281/zenodo.19642848 |
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| _version_ | 1866901339198455808 |
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| author | Christoffer, Alexander |
| author_facet | Christoffer, Alexander |
| contents | <p>This paper proposes that actively regulated growth systems — from mammalian cells to giant single-celled organisms to the observable universe — converge on a shared three-component architecture (~70% passive expansion medium, ~25% structural scaffold, ~5% active machinery) and a conserved set of organisational features.</p> <p>The framework generates 12 testable predictions, of which 3 are unique. One prediction (Einasto shape parameter match for microtubule density) was pre-registered, tested against real data from the Allen Cell Explorer, and falsified — the negative result is reported in full. The strongest thread identifies black holes as cosmic lysosomes, supported by Bluck et al. (2023) finding that black hole mass — not accretion rate — predicts galaxy quenching, mirroring mTOR regulation precisely.</p> <p>Research conducted using Claude (Anthropic) under a custom research protocol; supplementary materials include all analysis code, pre-registration, and raw data the negative result is reported in full. The strongest thread identifies black holes as cosmic lysosomes, supported by Bluck et al. (2023) finding that black hole mass — not accretion rate — predicts galaxy quenching, mirroring mTOR regulation precisely.</p> <p>All analysis code, pre-registration documents, and raw data are available as supplementary material. Full methodology — including the custom research protocol, adversarial review process, and LLM-assisted analysis pipeline — is documented in the paper and supplementary timeline.</p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19642848 |
| institution | Zenodo |
| language | eng |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | The Universe as a Living System: A Heuristic Framework Comparing Actively Regulated Growth Systems Across Scales Christoffer, Alexander cross-scale biology dark matter dark energy black holes lysosomes cytoskeleton three-component architecture heuristic framework pre-registration actively regulated growth systems <p>This paper proposes that actively regulated growth systems — from mammalian cells to giant single-celled organisms to the observable universe — converge on a shared three-component architecture (~70% passive expansion medium, ~25% structural scaffold, ~5% active machinery) and a conserved set of organisational features.</p> <p>The framework generates 12 testable predictions, of which 3 are unique. One prediction (Einasto shape parameter match for microtubule density) was pre-registered, tested against real data from the Allen Cell Explorer, and falsified — the negative result is reported in full. The strongest thread identifies black holes as cosmic lysosomes, supported by Bluck et al. (2023) finding that black hole mass — not accretion rate — predicts galaxy quenching, mirroring mTOR regulation precisely.</p> <p>Research conducted using Claude (Anthropic) under a custom research protocol; supplementary materials include all analysis code, pre-registration, and raw data the negative result is reported in full. The strongest thread identifies black holes as cosmic lysosomes, supported by Bluck et al. (2023) finding that black hole mass — not accretion rate — predicts galaxy quenching, mirroring mTOR regulation precisely.</p> <p>All analysis code, pre-registration documents, and raw data are available as supplementary material. Full methodology — including the custom research protocol, adversarial review process, and LLM-assisted analysis pipeline — is documented in the paper and supplementary timeline.</p> |
| title | The Universe as a Living System: A Heuristic Framework Comparing Actively Regulated Growth Systems Across Scales |
| topic | cross-scale biology dark matter dark energy black holes lysosomes cytoskeleton three-component architecture heuristic framework pre-registration actively regulated growth systems |
| url | https://doi.org/10.5281/zenodo.19642848 |