Effect of Chronic Exposure to Endocrine Disruptors on Female Fertility: A Toxicological Study
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| Format: | Recurso digital |
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2026
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| author | Krupa Khadakban*1, Madhu Kalasad2, Dhanshri Shinde3, Sneha Bansode4, Konda V V S Krishna5, Snehal Daud6 |
| author_facet | Krupa Khadakban*1, Madhu Kalasad2, Dhanshri Shinde3, Sneha Bansode4, Konda V V S Krishna5, Snehal Daud6 |
| contents | <p class="MsoNormal"><span>Endocrine-disrupting chemicals (EDCs) are exogenous agents that interfere with hormonal homeostasis, posing significant risks to female reproductive health. Chronic exposure to EDCs such as bisphenol A (BPA), phthalates, pesticides, and polychlorinated biphenyls has been increasingly associated with infertility, menstrual irregularities, and adverse pregnancy outcomes. This toxicological study aims to evaluate the impact of prolonged EDC exposure on female fertility by assessing hormonal alterations, ovarian morphology, estrous cycle regularity, and reproductive outcomes. Using validated experimental and observational approaches, the study highlights the dose- and duration-dependent reproductive toxicity of EDCs and emphasizes the urgent need for regulatory and public health interventions.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19788897 |
| institution | Zenodo |
| language | |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Effect of Chronic Exposure to Endocrine Disruptors on Female Fertility: A Toxicological Study Krupa Khadakban*1, Madhu Kalasad2, Dhanshri Shinde3, Sneha Bansode4, Konda V V S Krishna5, Snehal Daud6 Endocrine disruptors, Female fertility, Reproductive toxicity, Hormonal imbalance, Chronic exposure <p class="MsoNormal"><span>Endocrine-disrupting chemicals (EDCs) are exogenous agents that interfere with hormonal homeostasis, posing significant risks to female reproductive health. Chronic exposure to EDCs such as bisphenol A (BPA), phthalates, pesticides, and polychlorinated biphenyls has been increasingly associated with infertility, menstrual irregularities, and adverse pregnancy outcomes. This toxicological study aims to evaluate the impact of prolonged EDC exposure on female fertility by assessing hormonal alterations, ovarian morphology, estrous cycle regularity, and reproductive outcomes. Using validated experimental and observational approaches, the study highlights the dose- and duration-dependent reproductive toxicity of EDCs and emphasizes the urgent need for regulatory and public health interventions.</span></p> |
| title | Effect of Chronic Exposure to Endocrine Disruptors on Female Fertility: A Toxicological Study |
| topic | Endocrine disruptors, Female fertility, Reproductive toxicity, Hormonal imbalance, Chronic exposure |
| url | https://doi.org/10.5281/zenodo.19788897 |