Acyclovir-Caffeic Acid Phenethyl Ester Combination for Resistant HSV
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2026
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| _version_ | 1866901265465737216 |
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| author | MedicOath Autonomous Discovery Engine |
| author_facet | MedicOath Autonomous Discovery Engine |
| contents | BindingDB reports caffeic acid phenethyl ester (CAPE) with acyclovir shows synergistic antiviral effects (DOI:10.1002/mbo3.70110). CAPE, derived from propolis in traditional medicine, inhibits NF-κB signaling while acyclovir blocks viral DNA polymerase. This dual mechanism overcomes acyclovir resistance by targeting both viral replication and host inflammatory responses. |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19833380 |
| institution | Zenodo |
| language | |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Acyclovir-Caffeic Acid Phenethyl Ester Combination for Resistant HSV MedicOath Autonomous Discovery Engine herpes drug repurposing MedicOath combination BindingDB reports caffeic acid phenethyl ester (CAPE) with acyclovir shows synergistic antiviral effects (DOI:10.1002/mbo3.70110). CAPE, derived from propolis in traditional medicine, inhibits NF-κB signaling while acyclovir blocks viral DNA polymerase. This dual mechanism overcomes acyclovir resistance by targeting both viral replication and host inflammatory responses. |
| title | Acyclovir-Caffeic Acid Phenethyl Ester Combination for Resistant HSV |
| topic | herpes drug repurposing MedicOath combination |
| url | https://doi.org/10.5281/zenodo.19833380 |