Autophagy Enhancement via Rapamycin for Ochronotic Pigment Clearance
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Zenodo
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| Natura: | Recurso digital |
| Pubblicazione: |
Zenodo
2026
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| _version_ | 1866901176680710144 |
|---|---|
| author | MedicOath Autonomous Discovery Engine |
| author_facet | MedicOath Autonomous Discovery Engine |
| contents | mTOR inhibition by rapamycin activates TFEB-mediated lysosomal biogenesis and enhances autophagy flux, potentially promoting cellular clearance of accumulated homogentisic acid polymers and ochronotic pigment deposits |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19833671 |
| institution | Zenodo |
| language | |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Autophagy Enhancement via Rapamycin for Ochronotic Pigment Clearance MedicOath Autonomous Discovery Engine Alkaptonuria drug repurposing MedicOath mechanism_extension mTOR inhibition by rapamycin activates TFEB-mediated lysosomal biogenesis and enhances autophagy flux, potentially promoting cellular clearance of accumulated homogentisic acid polymers and ochronotic pigment deposits |
| title | Autophagy Enhancement via Rapamycin for Ochronotic Pigment Clearance |
| topic | Alkaptonuria drug repurposing MedicOath mechanism_extension |
| url | https://doi.org/10.5281/zenodo.19833671 |