Origin and Evolution of Oncogene Amplifications and Complex Genomic Rearrangements in Pancreatic Cancer

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Main Author: Jose Espejo Valle-Inclan
Format: Recurso digital
Published: Zenodo 2026
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author Jose Espejo Valle-Inclan
author_facet Jose Espejo Valle-Inclan
contents This Data Management Plan (DMP) outlines the data lifecycle for the computational project detailing the origin and evolution of complex genomic rearrangements in pancreatic cancer. The purpose of this DMP is to define the protocols for securely transferring, processing, and managing sensitive human genomic data across a meta-cohort of 1,000 Pancreatic Cancer Whole-Genome Sequencing (WGS) samples utilizing the Portuguese National Advanced Computing Network (RNCA). It details the strict 'stage, process, and prune' batching strategy implemented to comply with HPC storage quotas (50 TB max), ensures strict adherence to external Data Access Committee (DAC) regulations regarding the secure deletion of raw patient files, and establishes the framework for publishing aggregated, non-identifiable analytical results in accordance with FAIR and Open Science principles.
format Recurso digital
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institution Zenodo
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publishDate 2026
publisher Zenodo
record_format zenodo
spellingShingle Origin and Evolution of Oncogene Amplifications and Complex Genomic Rearrangements in Pancreatic Cancer
Jose Espejo Valle-Inclan
This Data Management Plan (DMP) outlines the data lifecycle for the computational project detailing the origin and evolution of complex genomic rearrangements in pancreatic cancer. The purpose of this DMP is to define the protocols for securely transferring, processing, and managing sensitive human genomic data across a meta-cohort of 1,000 Pancreatic Cancer Whole-Genome Sequencing (WGS) samples utilizing the Portuguese National Advanced Computing Network (RNCA). It details the strict 'stage, process, and prune' batching strategy implemented to comply with HPC storage quotas (50 TB max), ensures strict adherence to external Data Access Committee (DAC) regulations regarding the secure deletion of raw patient files, and establishes the framework for publishing aggregated, non-identifiable analytical results in accordance with FAIR and Open Science principles.
title Origin and Evolution of Oncogene Amplifications and Complex Genomic Rearrangements in Pancreatic Cancer
url https://doi.org/10.5281/zenodo.19895704