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2026
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| Accès en ligne: | https://doi.org/10.5281/zenodo.19916229 |
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| _version_ | 1866901378860843008 |
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| author | Dr Elizebeth Paulin Dr Pillai Biju Sukumaran Dr. P. Roy John |
| author_facet | Dr Elizebeth Paulin Dr Pillai Biju Sukumaran Dr. P. Roy John |
| contents | <pre><strong><em><span>Abstract</span></em></strong></pre> <pre><em><span>Prostate involvement by non-Hodgkins lymphoma is rare and may clinically mimic benign prostatic hyperplasia or adenocarcinoma. We report a case of disseminated diffuse large B cell lymphoma presenting with acute urinary retention on a middle age male, requiring catheterization. Serum prostate specific antigen was within normal limits. USG abdomen revealed grossly enlarged prostate gland protruding into base of bladder- approximately measuring 190 cc. when a relatively low PSA (o.46) for a 190cc sized gland led to clinical suspicion and patient underwent MRI scanning. On MRI, revealed a bulky prostate with mild infiltration to right pelvic floor muscles and metabolically active supra and infra diaphragmatic lymphadenopathy with extra nodal gastric involvement. Histopathology of prostatic tissue showed diffuse infiltration by atypical lymphoid cells and immunohistochemistry confirmed diffuse large B cell lymphoma. Bone marrow examination demonstrated trilineage haematopoiesis. The patient was referred for systemic chemotherapy. This case underscores the need to consider lymphoma in patients with acute urinary retention and normal PSA, as prompt recognition significantly alters management and prognosis. </span></em></pre> <pre><strong><em><span>Keywords: </span></em></strong><em><span>Acute urinary retention, Prostate lymphoma, Diffuse large B cell lymphoma, Extra nodal lymphoma, Lower urinary tract symptoms, Normal PSA, Disseminated lymphoma.</span></em></pre> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19916229 |
| institution | Zenodo |
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| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Acute Urinary Retention as the Initial Presentation of Disseminated Diffuse Large B Cell Lymphoma with Prostate Involvement Dr Elizebeth Paulin Dr Pillai Biju Sukumaran Dr. P. Roy John <pre><strong><em><span>Abstract</span></em></strong></pre> <pre><em><span>Prostate involvement by non-Hodgkins lymphoma is rare and may clinically mimic benign prostatic hyperplasia or adenocarcinoma. We report a case of disseminated diffuse large B cell lymphoma presenting with acute urinary retention on a middle age male, requiring catheterization. Serum prostate specific antigen was within normal limits. USG abdomen revealed grossly enlarged prostate gland protruding into base of bladder- approximately measuring 190 cc. when a relatively low PSA (o.46) for a 190cc sized gland led to clinical suspicion and patient underwent MRI scanning. On MRI, revealed a bulky prostate with mild infiltration to right pelvic floor muscles and metabolically active supra and infra diaphragmatic lymphadenopathy with extra nodal gastric involvement. Histopathology of prostatic tissue showed diffuse infiltration by atypical lymphoid cells and immunohistochemistry confirmed diffuse large B cell lymphoma. Bone marrow examination demonstrated trilineage haematopoiesis. The patient was referred for systemic chemotherapy. This case underscores the need to consider lymphoma in patients with acute urinary retention and normal PSA, as prompt recognition significantly alters management and prognosis. </span></em></pre> <pre><strong><em><span>Keywords: </span></em></strong><em><span>Acute urinary retention, Prostate lymphoma, Diffuse large B cell lymphoma, Extra nodal lymphoma, Lower urinary tract symptoms, Normal PSA, Disseminated lymphoma.</span></em></pre> |
| title | Acute Urinary Retention as the Initial Presentation of Disseminated Diffuse Large B Cell Lymphoma with Prostate Involvement |
| url | https://doi.org/10.5281/zenodo.19916229 |