TREATMENT OF AUTISM SPECTRUM DISORDER USING VITAMINS AND MICRONUTRIENTS: AN EXTENSIVE CLINICAL AND MECHANISTIC STUDY EVALUATE
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| Format: | Recurso digital |
| Sprache: | Englisch |
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2026
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| _version_ | 1866901548470108160 |
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| author | Ranjeet Kumar Mudit Kumar* Sagar Tomar Rohit Kumar Ashutosh Kumar Archana Maurya |
| author_facet | Ranjeet Kumar Mudit Kumar* Sagar Tomar Rohit Kumar Ashutosh Kumar Archana Maurya |
| contents | <p class="MsoNormal"><span>The neurodevelopmental illness known as autism spectrum disorder (ASD) has a complex etiology. Vitamin/mineral and targeted vitamin therapy trials have been prompted by the numerous reports of nutritional deficiencies and altered metabolism (oxidative stress, methylation abnormalities, immunological dysregulation) in ASD. Goal: Examine clinical data on vitamin-based and multivitamin therapy for core and related symptoms of ASD, summarizing safety, mechanisms, and suggestions for study and practice. Methods: Narrative evidence synthesis with a focus on large observational studies, systematic reviews/meta-analyses, and randomized controlled trials (RCTs). Results: Following multivitamin or tailored vitamin therapy (e.g., folinic acid, methyl cobalamin, vitamin D), small RCTs and a number of mechanistic and cohort studies indicate improvements in metabolic biomarkers and, in certain trials, clinician-rated or parent-reported symptoms.</span><span> </span><span>In observational studies and meta-analyses, prenatal folic acid/multivitamin consumption is consistently linked to a lower child risk of ASD. The overall quality of the data is inconsistent: there aren't many big, long-term RCTs, and conclusions can't be drawn with certainty because to differences in populations, supplements, dosage, and outcome measures. At conventional dosages, safety statistics are typically positive; nevertheless, large doses (or imbalanced supplements) have potential and actual dangers that need to be monitored.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_19923526 |
| institution | Zenodo |
| language | eng |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | TREATMENT OF AUTISM SPECTRUM DISORDER USING VITAMINS AND MICRONUTRIENTS: AN EXTENSIVE CLINICAL AND MECHANISTIC STUDY EVALUATE Ranjeet Kumar Mudit Kumar* Sagar Tomar Rohit Kumar Ashutosh Kumar Archana Maurya Autism spectrum disease multivitamin Mental Disorders Behaviors <p class="MsoNormal"><span>The neurodevelopmental illness known as autism spectrum disorder (ASD) has a complex etiology. Vitamin/mineral and targeted vitamin therapy trials have been prompted by the numerous reports of nutritional deficiencies and altered metabolism (oxidative stress, methylation abnormalities, immunological dysregulation) in ASD. Goal: Examine clinical data on vitamin-based and multivitamin therapy for core and related symptoms of ASD, summarizing safety, mechanisms, and suggestions for study and practice. Methods: Narrative evidence synthesis with a focus on large observational studies, systematic reviews/meta-analyses, and randomized controlled trials (RCTs). Results: Following multivitamin or tailored vitamin therapy (e.g., folinic acid, methyl cobalamin, vitamin D), small RCTs and a number of mechanistic and cohort studies indicate improvements in metabolic biomarkers and, in certain trials, clinician-rated or parent-reported symptoms.</span><span> </span><span>In observational studies and meta-analyses, prenatal folic acid/multivitamin consumption is consistently linked to a lower child risk of ASD. The overall quality of the data is inconsistent: there aren't many big, long-term RCTs, and conclusions can't be drawn with certainty because to differences in populations, supplements, dosage, and outcome measures. At conventional dosages, safety statistics are typically positive; nevertheless, large doses (or imbalanced supplements) have potential and actual dangers that need to be monitored.</span></p> |
| title | TREATMENT OF AUTISM SPECTRUM DISORDER USING VITAMINS AND MICRONUTRIENTS: AN EXTENSIVE CLINICAL AND MECHANISTIC STUDY EVALUATE |
| topic | Autism spectrum disease multivitamin Mental Disorders Behaviors |
| url | https://doi.org/10.5281/zenodo.19923526 |