THE IMPORTANCE OF THE IMMUNE SYSTEM IN THE PATHOGENESIS OF DIFFERENT CLINICAL FORMS OF VIRAL HEPATITIS A DISEASE

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Main Authors: Artikov, Ikrom Akhmedjanovich, Mirzajonova, Donokhon Bahodirovna
Format: Recurso digital
Published: Zenodo 2026
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author Artikov, Ikrom Akhmedjanovich
Mirzajonova, Donokhon Bahodirovna
author_facet Artikov, Ikrom Akhmedjanovich
Mirzajonova, Donokhon Bahodirovna
contents <p class="MsoNormal"><strong><em><span>Resume. </span></em></strong><em><span>Changes in TNF-</span></em><em><span>α</span></em><em><span> and HGF levels were identified in HAV infection, demonstrating a relationship between inflammatory and regenerative processes. An increase in TNF-</span></em><em><span>α</span></em><em><span> levels confirms its role as a mediator of inflammation, while elevated HGF levels reflect the response to hepatocyte damage and promote liver regeneration by enhancing hepatocyte proliferation. Higher HGF levels were associated with greater liver injury and an increased need for active regeneration.</span></em></p> <p class="MsoNormal"><strong><em><span>Keywords:</span></em></strong><em><span> viral hepatitis, immune system, liver, cachexin, growth factor, cytokines, imbalance.</span></em></p>
format Recurso digital
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institution Zenodo
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publishDate 2026
publisher Zenodo
record_format zenodo
spellingShingle THE IMPORTANCE OF THE IMMUNE SYSTEM IN THE PATHOGENESIS OF DIFFERENT CLINICAL FORMS OF VIRAL HEPATITIS A DISEASE
Artikov, Ikrom Akhmedjanovich
Mirzajonova, Donokhon Bahodirovna
<p class="MsoNormal"><strong><em><span>Resume. </span></em></strong><em><span>Changes in TNF-</span></em><em><span>α</span></em><em><span> and HGF levels were identified in HAV infection, demonstrating a relationship between inflammatory and regenerative processes. An increase in TNF-</span></em><em><span>α</span></em><em><span> levels confirms its role as a mediator of inflammation, while elevated HGF levels reflect the response to hepatocyte damage and promote liver regeneration by enhancing hepatocyte proliferation. Higher HGF levels were associated with greater liver injury and an increased need for active regeneration.</span></em></p> <p class="MsoNormal"><strong><em><span>Keywords:</span></em></strong><em><span> viral hepatitis, immune system, liver, cachexin, growth factor, cytokines, imbalance.</span></em></p>
title THE IMPORTANCE OF THE IMMUNE SYSTEM IN THE PATHOGENESIS OF DIFFERENT CLINICAL FORMS OF VIRAL HEPATITIS A DISEASE
url https://doi.org/10.5281/zenodo.20010297