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Bibliographic Details
Main Authors: Agrawal, Piyush, Bhalla, sherry, Usmani, Salman Sadullah, Singh, Sandeep, Chaudhary, Kumardeep, Raghava, Gajendra, Gautam, Ankur
Format: Recurso digital
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Published: Zenodo 2015
Online Access:https://doi.org/10.5281/zenodo.20086676
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  • <p><strong>CPPsite 2.0</strong> is an updated and significantly expanded version of the manually curated database of cell-penetrating peptides (CPPs). This resource is designed to support the scientific community in developing effective intracellular delivery vehicles for various therapeutic molecules, including drugs, proteins, and nucleic acids.</p> <p><strong>Web Server:</strong> <a href="https://webs.iiitd.edu.in/raghava/cppsite/" rel="nofollow">https://webs.iiitd.edu.in/raghava/cppsite/</a></p> <div class="markdown-heading"> <h2 class="heading-element">About the Database</h2> <a class="anchor" href="https://github.com/whodevrajverma/CPPsite2#about-the-database"></a></div> <p>Cell-penetrating peptides are short peptides (usually 10–30 amino acids) with the ability to gain access to the interior of almost any cell type. CPPsite 2.0 consolidates information from research papers and patents, providing a centralized platform to explore the sequences, modifications, and experimental validations of these peptides.</p> <ul> <li> <p><strong>Data Expansion:</strong> The current version holds approximately <strong>1,850 peptide entries</strong>, nearly doubling the content of the previous version.</p> </li> <li> <p><strong>Recent Curation:</strong> The updated data were curated from literature published between 2012 and 2015.</p> </li> <li> <p><strong>Focus on Diversity:</strong> A major focus of this update is the inclusion of CPPs with diverse chemical modifications.</p> </li> </ul>