The Triadic Oncology Ledger: Integrating Metabolic Flux, Informational Disorder, and Mechanical Remodeling as Coupled Drivers of Breast Cancer Progression and Therapy Resistance

Fuente: Zenodo

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Dettagli Bibliografici
Autore principale:	Cromwell, Tami Marie Cromwell, Tammy Marie Stomberg, Tami Stomberg
Natura:	Recurso digital
Lingua:	inglese
Pubblicazione:	Zenodo 2026
Soggetti:	breast cancer Triadic Oncology Ledger tumor microenvironment metabolic reprogramming metabolic flux informational disorder signaling entropy mechanobiology mechanotransduction extracellular matrix therapy resistance tumor heterogeneity immune evasion CAR-T cells solid tumors spatial transcriptomics systems oncology open-system framework tumor state-space Triadic Malignancy Score Φ∞ Ψ∞ Π∞ Breast cancer Cancer biology Systems oncology Tumor microenvironment Cancer metabolism Immuno-oncology Mechanobiology Spatial transcriptomics Therapy resistance Cellular therapy CAR-T therapy Tumor heterogeneity Extracellular matrix remodeling Signaling entropy Open-system modeling
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