ONE-POT TWO COMPONENT SYNTHESIS AND INVITRO STUDY OF BENZOXAZOLE PROMOTED BY CuI2
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| Format: | Recurso digital |
| Sprache: | Englisch |
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2026
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| _version_ | 1866901587246448640 |
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| author | Ch. Y. S. Rama Reddy1, K. Sravya1, Dr. N. Krishnarao1* |
| author_facet | Ch. Y. S. Rama Reddy1, K. Sravya1, Dr. N. Krishnarao1* |
| contents | <p><span>In this study, we present the design, synthesis, structural characterization, and biological evaluation of new benzoxazole from 2-aminophenol and substituted aldehydes in the presence of catalytic quantity of</span><span> CuI<sub>2<span> </span></sub><span>at room temperature.as possible therapeutic agents a two-component, one-pot cyclocondensation reaction using conventionally produced methods. Using mass spectrometry, <sup>1</sup>HNMR, and <sup>13</sup>CNMR, all substances were described. Furthermore, the desired compound outperformed the standard antibacterial activity by exhibiting notable against important bacterial strains, streptomycin and certain of its derivatives demonstrated moderate to high antibacterial effectiveness. These findings show that benzoxazole derivatives hold substantial promise for further development as medicinal agents.</span></span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_20204970 |
| institution | Zenodo |
| language | eng |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | ONE-POT TWO COMPONENT SYNTHESIS AND INVITRO STUDY OF BENZOXAZOLE PROMOTED BY CuI2 Ch. Y. S. Rama Reddy1, K. Sravya1, Dr. N. Krishnarao1* <p><span>In this study, we present the design, synthesis, structural characterization, and biological evaluation of new benzoxazole from 2-aminophenol and substituted aldehydes in the presence of catalytic quantity of</span><span> CuI<sub>2<span> </span></sub><span>at room temperature.as possible therapeutic agents a two-component, one-pot cyclocondensation reaction using conventionally produced methods. Using mass spectrometry, <sup>1</sup>HNMR, and <sup>13</sup>CNMR, all substances were described. Furthermore, the desired compound outperformed the standard antibacterial activity by exhibiting notable against important bacterial strains, streptomycin and certain of its derivatives demonstrated moderate to high antibacterial effectiveness. These findings show that benzoxazole derivatives hold substantial promise for further development as medicinal agents.</span></span></p> |
| title | ONE-POT TWO COMPONENT SYNTHESIS AND INVITRO STUDY OF BENZOXAZOLE PROMOTED BY CuI2 |
| url | https://doi.org/10.5281/zenodo.20204970 |