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| Format: | Recurso digital |
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Zenodo
2026
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| Online Access: | https://doi.org/10.5281/zenodo.20272160 |
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| _version_ | 1866901717921038336 |
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| author | Chavan, Swapnil |
| author_facet | Chavan, Swapnil |
| contents | <div>This dataset is derived from PubChem BioAssay AID 1159553, titled "qHTS assay to identify small molecule agonists of the retinoic acid receptor (RAR) signaling pathway".</div> <div> </div> <div> <div>The original assay is part of the Tox21 program and measures activation of retinoic acid receptor (RAR) signaling using a luciferase reporter gene assay under the control of retinoic acid response elements (RARE) in a cell-based system.</div> <div> </div> <div> <div>Original dataset statistics:</div> <div>- Tested compounds: 7,331 - Active (agonists): 364 - Inactive: 5,952</div> <div> </div> <div> <div>Data preprocessing:</div> <div>- Removed duplicate entries based on compound identifiers. - Resolved conflicting labels by excluding compounds with inconsistent activity annotations.</div> <div> </div> <div> <div>Final cleaned dataset:</div> <div>- Total compounds: 5,942 - Positive (agonists): 300 - Negative (inactive): 5,642</div> </div> </div> </div> </div> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_20272160 |
| institution | Zenodo |
| language | |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Cleaned dataset for PubChem AID 1159553: qHTS assay of retinoic acid receptor (RAR) agonists Chavan, Swapnil <div>This dataset is derived from PubChem BioAssay AID 1159553, titled "qHTS assay to identify small molecule agonists of the retinoic acid receptor (RAR) signaling pathway".</div> <div> </div> <div> <div>The original assay is part of the Tox21 program and measures activation of retinoic acid receptor (RAR) signaling using a luciferase reporter gene assay under the control of retinoic acid response elements (RARE) in a cell-based system.</div> <div> </div> <div> <div>Original dataset statistics:</div> <div>- Tested compounds: 7,331 - Active (agonists): 364 - Inactive: 5,952</div> <div> </div> <div> <div>Data preprocessing:</div> <div>- Removed duplicate entries based on compound identifiers. - Resolved conflicting labels by excluding compounds with inconsistent activity annotations.</div> <div> </div> <div> <div>Final cleaned dataset:</div> <div>- Total compounds: 5,942 - Positive (agonists): 300 - Negative (inactive): 5,642</div> </div> </div> </div> </div> |
| title | Cleaned dataset for PubChem AID 1159553: qHTS assay of retinoic acid receptor (RAR) agonists |
| url | https://doi.org/10.5281/zenodo.20272160 |