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| Formato: | Artículo científico |
| Lenguaje: | en |
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Universidade Estadual de Maringá
2018
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| Acceso en línea: | https://www.redalyc.org/articulo.oa?id=187158163039 https://www.redalyc.org/journal/1871/187158163039/ https://www.redalyc.org/journal/1871/187158163039/html/ https://www.redalyc.org/journal/1871/187158163039/187158163039.epub https://www.redalyc.org/journal/1871/187158163039/movil https://doi.org/10.4025/actascibiolsci.v40i1.37844 |
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- Toxicity of the goji berry fruit associated with artificial excipients and dried without additives Ana Paula Peron Débora Dayane Araújo de Moura Cleidiane Josefa dos Santos Veloso Valtânia Ana de Oliveira Eduarda Sousa e Silva Biología cytotoxicity genotoxicity Lycium barbarum L meristematic tissue natural pharmaceutical product The aim of this study was to evaluate the cytotoxic and genotoxic potential of goji berry fruit-based pharmaceutical powders obtained from three pharmaceutical laboratories. The product A was tested at concentrations of 0.012; 0.025 and 0.05 g mL-1, and B and C at concentrations 0.02; 0.04 and 0.08 g mL-1. It was also evaluated the tea of the dried goji berry fruit (non-additives) in the concentrations 0.035; 0.07 and 0.14 g mL-1 for comparison to the results obtained with powdered goji berry. Tea concentrations in the two exposure times did not cause inhibition of cell division nor cellular alterations to meristem tissues. For the industrialized goji products, all concentrations analyzed caused significant antiproliferative effect to the tissues evaluated at the shortest time of analysis. There were no significant cellular changes in tissues exposed to industrialized goji. Therefore, under the conditions of analysis, goji berry powder, at the three concentrations evaluated, was cytotoxic to root meristems. 2018 artículo científico 1679-9283 https://www.redalyc.org/articulo.oa?id=187158163039 https://www.redalyc.org/journal/1871/187158163039/ https://www.redalyc.org/journal/1871/187158163039/html/ https://www.redalyc.org/journal/1871/187158163039/187158163039.epub https://www.redalyc.org/journal/1871/187158163039/movil https://doi.org/10.4025/actascibiolsci.v40i1.37844 en http://www.redalyc.org/revista.oa?id=1871 Acta Scientiarum. Biological Sciences application/pdf Universidade Estadual de Maringá Acta Scientiarum. Biological Sciences (Brasil) Vol.40